Can exercise during childhood protect you against memory loss many decades later?Exercise early in life seems to have lifelong benefits for the brain,in rats at least.

     “This is an animal study,but it shows that physical activity at a young age is very important—not just for physical development,but for the whole lifelong track of cognitive（认知的）development during ageing,”says Martin Wojtowicz of the University of Toronto,Canada.“In humans,it may delay the appearance of Alzheimer's symptoms（阿茨海默氏症）,possibly to the point of preventing them.”

    Wojtowicz's team divided 80 young male rats into two equal groups,and placed running wheels in the cages of one group for a period of six weeks.Around four months later—when the rats had reached middle age—the team taught all the rats to connect an electric shock with being in a specific.When placed in the box,they froze with fear.

    Two weeks later,the team tested the rats in three situations: exactly the same box in the same room,the same box with the room arranged differently,and a completely different box in a different room.

    The rats without access to a running wheel when they were young now froze the same percentage of times in each of these situations,suggesting they couldn't remember which one was dangerous.But those that had been able to run in their youth froze 40 to 50 percent less in both changed box settings.

    "The results suggest the amount of physical activity when we're young,at least for rats,has influence on brain and cognitive health—in the form of better memories—when we're older,"says Arthur Kramer of Northeastern University in Boston,who has found that,in humans,exercise promotes the growth of new brain cells.

    Book 1: Diary of a Fly—By Doreen Cronin

    40 pages, US $15. 99

    This is the diary of a fly. The fly, when she's not landing on your head or swimming in your soup, is trying to escape her 327 siblings who are driving her crazy. Even though she's little—just like her best friends, Worm and Spider— she wants to be a superhero. This is the story of a little fly who's unafraid to dream big.

    Book 2: Iggy Peck, Architect—By Andrea Beaty

    32 pages, US $15.95

    This book is a story about a kid whose head teacher doesn't recognize his great talent (though he makes buildings out of anything at hand, including table cloths, fruit and chalk) until it saves her life. With Andrea Beatty's rhyming text and David Roberts's interesting illustrations (插图), it will charm creative kids everywhere.

    Book 3: The Chicken-Chasing Queen of Lamar County—By Janice N. Harrington

    40 pages, US $16.00

    Our character here loves to run after chickens, particularly Miss Hen, who's very fat. But, as all farming folks know, this is not a good way to produce happy, productive chickens. What will make her change her ways? The author is a professional storyteller and this book is full of fun, and has great illustrations.

Book 4: Cherry and Olive—By Benjamin Lacombe

    32 pages, US $16.95

    Children's books can quickly take little readers into new worlds, such as the big city, 1930s Georgia, or outer space. This book takes us on a little trip to some European capitals. Cherry is fat and likes books, and she has few friends until she meets a SharPei puppy (沙皮狗). She names it Olive. Through it she finds confidence and friendship. But what will happen when its owner returns?

    Depression(抑郁) can be a destructive illness, plaguing millions of people worldwide with feelings of sadness, hopelessness, and fatigue. Despite numerous antidepressant drugs, as many as a third of patients don't respond to medication. This has forced doctors to be more creative in finding different treatments for the condition.

    In the past two decades, researchers have tied depression to a seemingly unrelated condition: inflammation(炎症), the body's natural response to stress. It could rise from injury or inflection, or even emotional issues like an unhappy marriage or problems at work. Some amount of inflammation is generally beneficial, as it increases production of cytokines(致癌因子)，proteins that help us heal and protect us from the effects of overwork.

    But excessive cytokine levels, and the inflammation they bring on, could come at a cost—a number of studies suggests that high levels of cytokines could contribute to depression.

    Cytokines can reach the brain several ways: directly through the blood-brain barrier or indirectly by binding to nerve fibers elsewhere, which send signals to the brain to produce the inflammation molecules. In the brain, cytokines can disturb the production and release of several important signaling chemicals, including serotonin, dopamine and glutamate, which help control emotion, appetite, sleep, learning and memory. It's though that a lack of serotonin activity in the brain causes depression; most antidepressants increase the activity. But cytokines also have been shown to activate stress hormone signaling in the brain, which man also serve to develop depression.

    With all the evidence implicating inflammation in depression, doctors have been anxious to test anti-inflammatory drugs as a potential treatment. Four small studies published between 2006 and 2017 by research groups in Europe and Iran found that adults diagnosed with depression who took aspirin or another anti-inflammatory drug called Celecoxib, along with an antidepressant, got more relief from feelings of sadness, hopelessness, guilt and fatigue compared with those taking an antidepressant alone. However, Andrew Miller, a professor of psychiatry at Emory University, thought something was wrong in these small, limited studies. None of them looked at whether the participants had to have high levels of cytokines before they'd see a benefit from anti-inflammatory drugs.  "Unfortunately, much of the field has fallen into the trap of viewing inflammation as the be-all, end-all," Miller says. He and his colleagues wanted to see whether the effect of these drugs was limited to the depression patients with high cytokine levels, or if it helped all people diagnosed with depression.

    Let us begin by saying what causes our dreams. Our dreams do not come from another world. They are not messages from some outside source. They are not a look into the future, either.

    All our dreams have something to do with our feelings, fears, longings, wishes, needs and memories. If a person is hungry, or tired, or cold, his dreams may include a feeling of this kind. If the covers on your body, such as a quilt or a blanket, have slipped off your bed, you may dream that you are sleeping on ice or in snow. The material for the dream you will have tonight is likely to come from the experience you have today.

    So the subject of your dream usually comes from something that has effect on you while you are sleeping（feeling of cold, a noise, a discomfort, etc. ）and it may also use your past experiences and the wishes and the interests you have now. This is why children are likely to dream of fairies, older children of school examinations, hungry people of food, homesick soldiers of their families and prisoners of freedom.

    To show you how this is happening while you are asleep and how your needs and wishes can all be joined together in a dream, here is the story of the experiment. A man was asleep and the back of his hand was rubbed with a piece of absorbed cotton. He would dream he was in hospital and his charming girlfriend was visiting him, sitting on the bed and feeling his hand gently!

    There are some scientists who have made a special study of why we dream, what we dream and what those dreams mean. Their explanation of dreams, though a bit reasonable, is not accepted by everyone but it offers an interesting approach to the problem. They believe that dreams are mostly expressions of wishes that did not come true. In other words dreaming is a way of having your wishes carried out.

What makes preschoolers eat their vegetables? Raise their hand? Wait their turn? "Because I say so" is a comment that parents often repeat. But when it comes to getting kids to behave, a recent study by Duke University researchers suggests that the voice of adult authority isn't the only thing that matters. Around age three, fitting in with the group starts to count big too.

To understand what cause preschoolers to fall    in    line, the researchers conducted a test in a lab, where they invited 3.5-year-olds to help set up for a pretend tea party. Each of the 104 children was given a blue sticker (贴纸) to wear at the start of the study, and told that the people with that color sticker were part of the same team. Next the researchers watched as the children decided among different kinds of teas, snacks, cups and plates for the tea party, first on their own and then after listening to the choices of other team members.

Sometimes the other team members considered their choice as a matter of personal preference ("For my tea party today, I feel like using this snack.") Other times they presented it as a need shared by the whole group. ("For our tea parties today, we always use this kind of snack.")

After listening to the choices of others, most of the time the children stuck with their first choice. In other words, children who had said they felt like using, say, the cookie finally picked the cookie no matter what the other person said they were using. But 23% of the time the children changed their choice to accept someone else's. And when they did, they were more likely to go along with the other person when a choice was presented as a group need rather than just a personal preference. The finding held up even when the other person was another child, not an adult.

Developing and maintaining healthy friendships involves give-and-take. {#blank#}1{#/blank#}Expressing your feelings of affection and gratitude towards your friends is a powerful way to reinforce the connections you share with them. It is equally crucial for you to embody the qualities of a supportive and considerate friend as it is to be surrounded by individuals who embody these traits. By acknowledging and valuing the presence and contributions of your friends in your life, you not only nurture your relationships but also create an environment of mutual respect and understanding. This reciprocal appreciation can lead to deeper, more meaningful friendships that stand the test of time.

To nurture your friendships:

Be kind. This most-basic behavior remains the core of successful relationships.{#blank#}2{#/blank#} Every act of kindness and every expression of gratitude are deposits into this account, while criticism and negativity draw down the account.

Be a good listener.{#blank#}3{#/blank#} Let the other person know you are paying close attention through eye contact, body language and occasional brief comments such as, "That sounds fun." When friends share details of hard times or difficult experiences, be empathetic, but don't give advice unless your friends ask for it.

Open up. Build intimacy with your friends by opening up about yourself. Being willing to disclose personal experiences and concerns shows that your friend holds a special place in your life, and it may deepen your connection.

 {#blank#}4{#/blank#}Being responsible, reliable and dependable is key to forming strong friendships. You're your engagements and arrive on time. Follow through on commitments you've made to your friends. When your friends share confidential information, keep it private.

Make yourself available. {#blank#}5{#/blank#} Make an effort to see new friends regularly, and to check in with them in between meet ups. You may feel awkward the first few times you talk on the phone or get together, but this feeling is likely to pass as you get more comfortable with each other.