A bite from a tsetse fly (采采蝇) is an extremely unpleasant experience. It is not like a mosquito, which can put its thin mouthpart directly into your blood, often without you noticing. In contrast, the tsetse fly's mouth has tiny saws on it that saw into your skin on its way to suck out your blood.

    To make matters worse, several species of tsetse fly can transmit diseases. One of the most dangerous is a parasite that causes ＂sleeping sickness＂, or ＂human African trypanosomiasis＂to give it its official name. Without treatment, an infection is usually fatal.

    Like so many tropical diseases, sleeping sickness has often been neglected by medical researchers. However, researchers have long endeavored to understand how it avoids our bodies' defence mechanisms. Some of their insights could now help us eliminate sleeping sickness altogether.

    There are two closely-related single-celled parasites that cause this deathly sleep: Trypanosoma brucei rhodesiense and T. b. gambiense. The latter is far more common: it is responsible for up to 95% of cases, mostly in western Africa. It takes several years to kill a person, while T. brucei rhodesiense can cause death within months. There are still other forms that infect livestock.

    After the initial bite, sleeping sickness symptoms often start with a fever, headaches and aching muscles. As the illness goes on, those infected become increasingly tired, which is where it gets its name. Personality changes, severe confusion and poor coordination can also happen.

    While medication does help, some treatments are toxic and can themselves be deadly, especially if they are given after the disease has reached the brain.

    It is worth noting that sleeping sickness is no longer as deadly as it once was. In the early 20th Century several hundred thousand people were infected each year. By the 1960s the disease was considered ＂under control＂ and had reached very low numbers, making its spread more difficult. But in the 1970s there was another major epidemic, which took 20 years to control.

    Since then, better screening programmes and earlier interventions have reduced the number of cases dramatically. In 2009 there were fewer than 10,000 cases for the first time since records began, and in 2015 this figure dropped to fewer than 3,000, according to the latest figures from the World Health Organisation. The WHO hopes the disease will be completely eliminated by 2020.

    While this decline looks positive, there may be many more cases that go unreported in rural Africa. To eliminate the disease completely, infections have to be closely monitored.

    More problematically, a series of new studies have shown that the parasite is more complicated than previously believed.

    Sleeping sickness has always been considered —— and diagnosed —— as a blood disease, because T. brucei parasites can readily be detected in the blood of its victims.

    China's cancer researcher Zhu Chen, together with two French researchers Anne Dejean and Hugues de Thé, received Sjoberg Prize 2018 in Stockholm Concert Hall, Sweden on Friday.

    “We used wisdom from both Chinese and Western medicine and offered a cure to one of the most deadly cancers,” Chen told Xinhua, “I feel that Chinese medicine has potential to contribute more to human health. It struggles for benefiting all mankind. It's a language of peace, and of development and progress.” Chen recalled the cooperation with the two French researchers for over 30 years.

    This year's Sjoberg winners have developed a new and targeted treatment for a specific form of blood cancer called acute promyelocytic leukaemia (急性早幼粒白血病). It was once one of the deadliest forms of cancer, but it is now possible to cure nine out of ten patients who receive the new treatment. The winners have made this revolutionary development possible by methodically mapping the molecular mechanisms responsible for the disease.

    The Prize is awarded by the Royal Swedish Academy of Sciences and is funded (资助)by the Sjoberg Foundation. The foundation, with a donation of 2.5 billion US dollars, was founded in 2016, and serves to promote scientific research that focuses on cancer, health and the environment.

    The Prize is an annual international prize in cancer research awarded to individual researchers or research groups. The prize amounts to one million US dollars, of which 100,000US dollars is the prize sum and 900,000US dollars is funding for future research.

AFTER AMAZON ECHO MISFIRE, WAYS TO PROTECT YOUR OWN PRIVACY

    Revelations that an Amazon Echo smart speaker accidentally sent a family's private conversation to an acquaintance highlights some unexpected privacy risks of new voice-enabled technologies. There's no way to totally avoid these sorts of privacy risks except unplugging them entirely, but you can minimize the unpleasant privacy surprises with these tips:

    KILL THE MIC: Most smart speakers have a physical button to disable the microphone, so a private conversation can't be recorded to begin with. You can hit that when you're having sensitive conversations. It doesn't make sense to keep the mic disabled throughout the day, though.

    LIMIT THE MIC: Disabling the microphone isn't practical on a smartphone, but you can limit what apps have access to it. Go to the settings and turn off mic access to all but essential apps such as voice recorders or video conferencing.

    ABOUT THAT CAMERA: Facebook CEO Mark Zuckerberg famously puts a piece of tape over his laptop's camera to prevent spying if anyone were to hack his device. Buy yourself a roll. Or use bandages. If you have a home-security camera that's connected to the Internet, turn the camera to the wall when you're home.

    BLOCK THE SIGNALS: For smartphones and other gadgets you carry with you, a "Faraday bag" can help prevent unwanted spying. The good ones will block cellular and other signals, meaning privacy-compromising information such as your location won't leak out either. However, your phone won't get any calls while it's in the bag.

    Of course, the safest approach is not to buy a new gadget in the first place. That might not be practical these days, but do you really need a smart speaker or a television set that's connected to the Internet?

A popular saying goes, “Sticks and stones may break my bones, but words will never hurt me.” However, that's not really true. Words have the power to build us up or tear us down. It doesn't matter if the words come from someone else or ourselves — the positive and negative effects are just as lasting.

    We all talk to ourselves sometimes. We're usually too embarrassed to admit it, though. In fact, we really shouldn't be because more and more experts believe talking to ourselves out loud is a healthy habit.

    This “self-talk” helps us motivate ourselves, remember things, solve problems, and calm ourselves down. Be aware, though, that as much as 77% of self-talk tends to be negative. So in order to stay positive, we should only speak words of encouragement to ourselves. We should also be quick to give ourselves a pat on the back. The next time you finish a project, do well in a test, or finally clean your room, join me in saying “Good job!”

    Often, words come out of our mouths without us thinking about the effect they will have. But we should be aware that our words cause certain responses in others. For example, when returning an item to a store, we might use warm, friendly language during the exchange. And the clerk will probably respond in a similar manner. Or harsh（刻薄的）and critical language will most likely cause the clerk to be defensive.

    Words possess power because of their lasting effect. Many of us regret something we once said. And we remember unkind words said to us! Before speaking, we should always ask ourselves: Is it loving? Is it needed? If what we want to say doesn't pass this test, then it's better left unsaid.

    Words possess power: both positive and negative. Those around us receive encouragement when we speak positively. We can offer hope, build self-esteem（自尊）and motivate others to do their best. Negative words destroy all those things. Will we use our words to hurt or to heal? The choice is ours.

    ⒈Part of northern California had become an inferno(火海) in the latest big fire. A nearby town, Paradise, was reduced to ash. Nearly 50 people are confirmed dead and over 200 missing. Six of the ten most destructive fires in California's history have occurred in the past decade. Last year was the most destructive year on record, until this year. Why is the Golden State so flammable?

    ⒉There are three reasons why California has been surrounded by flames. First, the climate is becoming warmer. This has led to snow melting earlier, drier landscapes and a longer season when fires are likely to occur.

    ⒊A second reason is that more people live in flammable places. Since the 1990s 60% of new homes in California, Washington and Oregon have been built in spaces next to nature. These areas, which environmentalists call the "wildland-urban interface", are at higher risk of wildfire.

    ⒋A third reason is that there is more fuel. Before western settlers arrived, fires used to happen often and naturally, which made less fuel available for future fires. For the past century fires have been controlled well. This has led to a build-up of dry brush, and makes the average wildfire much likelier to turn into a big one.

    ⒌Putting out the flame is the most immediate task for California, but not the last. Many survivors will want to rebuild their homes exactly where they were. Californians will also want to ensure that utility companies(公用事业公司) are acting and investing responsibly. Investigations into what caused the fire are still going on, but some reports suggest it may have begun with sparks (火花) from lines owned by an electricity company.

    Want to find a job? Now read the following advertisements.

    FAIRMONT HOTEL

    Five waiters and Ten Waitresses

—Aged under 22

—At least high school graduate

—Good looking; men at least 1.72 meters tall and women 1.65

—Those knowing foreign languages preferred

—Paid 1600—2200 dollars per month

    One Secretary

—Aged under 30

—Female preferred

—Good at writing and skilled at computer

    If interested, call 465-4768 or write to: Mr. Jack Hundris Room 0825, Fairmont Hotel

    567 Wood Street, San Markers, 78003

    Fax: 6954828

    WILSON BOOKSTORE

    Accountant(会计)

—Aged between 25 and 40

—With an experience of at least two years

—With a degree and an accountant certificate(证书)

—Paid 3000-4000 dollars monthly

—With a knowledge of computer

    Salesclerk

—Basic education of 12 years or more

—Good at computer

—Paid 1800-2200 dollars monthly

    Tel: 447-4398

    Fax: 3485269