Too much work and too much wine go together like biscuits and cheese, a new international studies finds. Employees who work more than 48 hours a week are 11 percent more likely to over-consume (过渡消费) alcohol than those who work standard time, Finnish researchers say. The study looked at more than 300,000 people in Australia, Europe and North America. No differences were seen between men and women, says the study, published in the British Medical Journal.

    Risky alcohol consumption is considered as more than 14 drinks a week for women and more than 21 drinks a week for men. About 20 percent of Australians drink at levels that put them at risk of lifetime harm from injury or disease. Drinking alcohol can affect the liver or cause brain damage, heart disease, high blood pressure and increase the risk of many cancers.

    Study author Marianna Virtanen said while alcohol might help ease the stress of working long periods of time, risky consumption could lead to difficulties in the workplace, such as poor performance. The European Union Working Time Directive ensures that workers in EU countries have the right to work no more than 48 hours a week, including overtime. “ But many people , for example well-educated managers and professionals, work much longer hours to achieve faster promotions (晋升), salary increases, and more control over work and employment,” said Prof. Virtanen from the Finnish Institute of Occupational Health.

    More than loo genes are related with increased risk of developing schizophrenia（精神分裂症）,bipolar disorder （躁郁症）and alcoholism（酗酒）,confirms a large study published in the recent issue of the British scientific journal Nature.

    The world's largest study into the genetic basis of mental illnesses was led by researchers from British universities,including University College London (UCL),Cardiff University and King's College London (KCL).

    Researchers believe that they are now much closer than before to understanding the complex biological causes, which make some people being at high risk of developing mental illnesses.They also believe that these findings could lead to new treatments.

    The researchers analyzed the DNA of about 37,000 patients with schizophrenia,bipolar disorder or alcoholism, and compared the smallest genetic changes to those found in about 113,000 healthy people.They then identified about 128 independent genetic variants（变体）at 108 locations on the human chromosomes（染色体）that contribute significantly to developing schizophrenia—83 of these sites have never before been linked to the illness,according to scientists.

    For example,people with the variant of the GRM3 gene,thought to be important in brain signaling,are around 2 to 3 times more likely to develop schizophrenia or alcohol dependence.The variant,which is found in approximately one in every 200 people,is also associated with a three times risk of developing bipolar disorder.

    "We could be looking at the next big drug target for treating mental illness,"Professor David Curtis from UCL, co-author of the paper,said."The work opens up new ways to prevent and treat mental illnesses by revealing the mechanisms involved in their development."

    The summer holidays are coming up. It's time to fill the bookshelves with quality literature for the kids. Here are some great books.

    Josephine Wants to Dance by Jackie French

    Price: $14.99 (for ages 4+)

    Josephine is a kangaroo who loves to dance. Her little brother, Joey, tells her that kangaroos don't dance; they jump. But Josephine continues to point her toes and leap through the air. When a ballet group comes to town and the lead ballerina (芭蕾舞演员) is injured, Josephine is called upon to help save the day. Can she do it, and, more importantly, does it matter that she's a kangaroo?

    House of Secrets by Chris Columbus

    Price: $19.99 (for ages 9+)

    The Walker kids —Caroline, Brendan and Nell—may have saved the world, but they can't save their home and must leave Kristoff House. Things can't get any worse, but then it turns out that the Wind Witch is still alive and planning an attack. To defeat her, the Walkers must return to the book world. The Walkers always help each other, but they must do it alone in their most important mission yet. And this time, if they fail, there's no chance of coming back.

    Edge of Extinction Book 1 by Laura Martin

    Price: $16.00 (for ages 9+)

    If you like The Land of the Dinosaurs, you will love this book. Two hundred years ago, the first dinosaur was successfully cloned (克隆). Soon after, humans realized they'd made a big mistake. Thirteen-year-old Sky Mundy's father suddenly disappeared five years ago. Along with her best friend， Shawn， she steps out into the world above --a world of dinosaurs --to look for him. Then she learns that everything she's been taught has been a lie.

    He has been called France's youngest leader since Napoleon Bonaparte. Emmanuel Macron, age 39, swept to victory in France's second-round of presidential election which was held on May 7, 2017. He defeated Marine Le Pen by a large margin of 62% of votes. He was inaugurated (就职) as President.

    Both of Macron's parents were doctors, and he attended one of the most prestigious (有声望的) schools in France, Lycee Henri Ⅳ. From there, he became an investment banker and economy minister. Unlike the other presidential candidates, he has always worked outside of the government.

    In April 2016, he created his own political movement, called En Marche! (On the Move!), recruiting (招募) more than 20,000 members. His party's ideals were neither right-or left-winged, but more independent. As his party became more and more successful, Macron began to think about presidency, something he'd always been interested in. In November 2016, he announced his decision to run in the 2017 election.

    Macron's campaign relied on his political movement. He struggled to win votes from both parties in France, as well as from the working class. In addition, he was the only candidate that was pro-EU, or supportive of European Union.

    While in office, Macron's biggest focus will be on improving the economy. A total of €50 billion will be dedicated to job training and creating green and sustainable energy. Macron also plans to cut down on corporate taxes, improve the public education system, and lower the unemployment rate by 2.7%.

    Following the election is the selection of the president's cabinet (内阁). The Prime Minister position was given to Edouard Philippe, mayor of Northern Le Havre. However, Macrons cabinet is surprising—one France has never seen before: a gender-balanced cabinet. Out of the 22 seats available, 11 will be taken by women and 11 will be filled by men. This percentage is much higher than other European countries.

    With each change of leadership come new ideals and changes to the country. Macron needs a parliament (议会) that will support his hopes and dreams for the future of France.

    FaceApp has taken the world by storm, giving users the chance to see themselves age through its algorithm. 12.7 million people—some three million more than the population of New York City—reportedly downloaded it in one seven-day period last month.

    Although the Russian app has become known for its privacy issues, the more interesting lesson of our FaceApp fling (尽情玩乐)is what it tells us about our society—and our future lives. It turns out we are more interested in aging than we realized. I'm surprised by this. Most younger people are in denial (否认)about old age, doing almost nothing to prepare for it. We rarely have a chance to plan for the future, with increasing time and financial pressures. Those pressures bring sacrifices that we may not always want to make: we can no longer afford to spend the time or the money needed to look after our elderly parents.

    As a family doctor, I can see the loneliness epidemic developing. Elderly patients come to see me with no particular illness, no clear medical issue. After a few minutes of the consultation, I understand why: they're not sick, and often they don't feel sick. They just need someone—anyone-to talk to.

    Although loneliness has no medical classification, the health effects are real: the result of loneliness and isolation can be as harmful to our health as smoking 15 cigarettes a day, and is more damaging than obesity. But loneliness does not come with nearly enough health warnings.

    So what next? Since 1980, we are living on average 10 years longer. At the same time, people are having fewer and fewer children, and they are having them much later in life. The snake of a world class health service is eating its own tail; its care is prolonging (延长) people's lives, but as the ratio of pensioners(退休人员)to working -age people increases, there are fewer taxpayers to fund that very health service.

    Into this void have stepped NGOs, charities and volunteers. But in the long term, the only way to truly help the oldest meters of our society is to go back to the traditional values of intergenerational(两代间的) cooperation—often under same roof. Ultimately, we will need to evolve towards a culture where elderly care is treated the same as childcare, where employers recognize the duty of someone with an elderly parent the same way they recognize those of someone with a newborn child.

    136 Crestview Circle

    Dover, Connecticut

    January 16, 2015

    Gander's Furniture Store

    Stamford, Connecticut, 09876

    Dear Sir,

    I am writing about your January bill, which I am returning with this letter. I am not going to pay this bill. Last month I bought a table and four chairs for $65.50. They were sent to me on December 18. That night one leg of the table broke while my wife was putting our dinner on it. It fell on one of the chair, and that broke, too. Our $ 2.50 steak landed on the floor, and the dog ate it.

    I spoke to the salesmen who had sold me the table and the chairs. He told me to write you a letter. I wrote you on December 20, saying that I was not going to pay for the furniture. On December 21 some men came and took it back to the store.

    Please do something about your records. I do not want to receive another bill for the furniture which I returned.

Yours truly,

Alberts Robbins