Exercise may help to safeguard the mind against depression through previously unknown effects on working muscles, according to a new study involving mice.

    Mental health experts have long been aware that even mild, repeated stress can contribute to the development of depression and other mood disorders in animals and people. Scientists have also known that exercise seems to cushion against depression. But precisely how exercise, a physical activity can lessen someone's risk for depression, a mood state, has been mysterious. So for the new study, researchers at the Karolinska Institute in Stockholm studied the brains and behavior of mice in a complicated and novel fashion.

    We can't ask mice if they are feeling cheerful or in low spirits. Instead, researchers have pictured certain behaviors that indicate depression in mice. If animals lose weight, stop seeking out a sugar solution when it's available — because, probably, they no longer experience normal pleasures — or give up trying to escape from the cold-water zone just freeze in place, they are categorized as depressed. And in the new experiment, after five weeks of frequent but low-level stress, such as being lightly shocked, mice displayed exactly those behaviors. They became depressed.

    The scientists could then have tested whether exercise blunts (延缓) the risk of developing depression after stress by having mice run first. But, frankly, from earlier research, they wanted to know how, so they bred pre-exercised mice. A wealth of earlier research by these scientists and others had shown that aerobic exercise, in both mice and people, increases the production within muscles of an enzyme (酶) called PGC-1alpha. The Karolinska scientists suspected that this enzyme somehow creates conditions within the body that protect the brain against depression. Then, the scientists exposed the animals, which without exercising, were in high levels of PGC-1alpha to five weeks of mild stress. The mice responded with slight symptoms of worry. But they did not develop depression. They continued to seek out sugar and fought to get out of the cold-water zone. Their high levels of PGC-1alpha appeared to make them depression-resistant. Finally, to ensure that these findings are relevant to people, the researchers had a group of adult volunteers complete three weeks of frequent endurance training, consisting of 40 to 50 minutes of moderate cycling or jogging. The scientists conducted muscle biopsies (活体检查) before and after the program and found that by the end of the three weeks, the volunteers' muscle cells contained substantially more PGC-1alpha than at the study's start. The finding of these results, in the simplest terms, is that “you reduce the risk of getting depression when you exercise,” said Maria Lindskog, a researcher at the Karolinska Institute.

    One Moore Elementary school teacher is showing students the importance of communication through “shout-outs”. Third Grade Moore Elementary Teacher Lindsey Winders said a shout-out is a compliment(称赞) that students can say or write down. “Like, 'hey I noticed you doing a really great job solving your math problems yesterday. I wanted to make sure you know that I saw you do that,'” Winders said.

    Winders said she makes sure she is giving shout-outs to her students every day. “I might write them a sticky note, or write them a quick little note in their planner. I might just say it to them on their way into the classroom or on their way out of the classroom, but most importantly I try to do it every day,” Winders said.

    In addition to the compliments, Winders has the students greet(问候) each other every morning during morning meeting. She will have students give examples to the class of how to communicate in different settings(场景). Third grade student Nayelli Moranchel said she had given at least six shout-outs this year. “It makes me happy, because they always write something back,” Moranchel said.

    Recently, Winders took it one step further and wrote a personalized note on each of her students' desk. “In our classroom, sometimes it can be challenging for me to give a compliment or a shout-out to each and every one of them in a way that feels equal(平等的) and valuable at the same time. So I decide that there is no better way than leaving a note on their desk that can stay for as long as they wants it to,” Winders said.

    Winders said it is encouraging when she sees her students copy the act, and give each other compliments without her guidance(指导).

    While every dog owner knows their dogs can read their moods perfectly, scientists have always been a little doubtful. Now thanks to some researchers at the University of Veterinary Medicine in Vienna, Austria, we finally have some convincing evidence.

    For this study, biologist Corson Miller and his team exposed eleven selected dogs to digital images of women that were either angry or happy. Half the dogs were rewarded for touching the screen when shown a happy face, while the other half given their treat for selecting those that appeared angry.

    Interestingly, the dogs were not provided with the entire face. Some dogs were shown only upper halves while the others observed lower halves. That's because the scientists believe humans show their eruptions on their entire face.

    After some training on how to recognize small differences like the wrinkles between the eyes or the changes in their shape that accompany the happy or angry expressions, the dogs were mostly able to identify the correct expression not only on a familiar face but on a strange face, the researchers concluded the dogs were smart enough to read human emotions.

    They also found those being trained to read angry expressions took a longer time to learn. They guess it may be because dogs find angry faces disgusting, causing them to back away quickly. However, once the smart dogs realized they were getting rewarded, the trepidation seemed to disappear. In fact, the dogs had such a good time playing the computer "game" that scientists had a hard time keeping them away from the touch screens after the study was completed.

    The researchers also noticed only dogs with a male owner had a harder time understanding the expressions correctly. Since the touched screen models were all females, this confirmed what has been observed in previous studies-dogs are more efficient at reading facial expressions of people that are the same gender as their owner.

Forget Cyclists, Pedestrians are Real Danger

    We are having a debate about this topic. Here are some letters from our readers.

    Yes, many cyclists behave dangerously. Many drivers are disrespectful of cyclists. But pedestrians are probably the worse offenders.

    People of all ages happily walk along the pavement with eyes and hands glued to the mobile phone, quite unaware of what is going on around them. They may even do the same thing while crossing a road at a pedestrian crossing or elsewhere. The rest of us have to evade (避让) them or just stand still to wait for the unavoidable collision.

    The real problem is that some pedestrians seem to be, at least for the moment, in worlds of their own that are, to them, much more important than the welfare of others.

——Michael Horan

    I loved the letter from Bob Brooks about cyclists (Viewpoints, May 29). I am afraid they seem to think they own the roads.

    I was walking across Altrincharn Road one morning when a cyclist went round me and on being asked what he was doing he shouted at me.

    The government built a cycle lane on the road but it is hardly used.

    The police do nothing. What a laugh they are!

    The cyclists should all have to be made to use the cycle lanes and wear helmets, fluorescent (发荧光的)jacket and tights at night and in the morning. They should pay some sort of tax and be fined for not wearing them.

——Carol Harvey

    Cyclists jump on and off pavements (which are meant for pedestrians), ride at speed along the pavements, and think they have a special right to go through traffic lights when they are on red.

    I was almost knocked down recently by a cyclist riding on the pavement when there was a cycle lane right next to him.

    Other road users, including horse riders, manage to obey the rules so why not cyclists?

    It's about time they had to be registered and insured, so when they do hit a pedestrian or a vehicle, or cause an accident, at least they can be traced and there might be an opportunity to claim.

——JML

    Write to Viewpoints of the newspaper.

The hens look up at me from their nesting boxes. They seem slightly annoyed but unsurprised. A child runs up, pushes one of the chickens aside, and snatches two eggs. Around me, a half-dozen more children and adults collect eggs while a half-dozen others hand-feed dried mealworms to birds flocking around our ankles. I reach for an egg from an empty nest. There is something perfect about the way it fits warmly in the palm of my hand before I transfer it into a pretty wire basket provided to me by my hosts. 

The egg harvest is a brief, carefully designed agritourism experience offering an experience of the labor rather than just having a bite of food. Snatching a few eggs and uprooting a few vegetables on the farm tour donˈt constitute a full dayˈs work, but it is also a useful reminder that food doesnˈt just magically appear on restaurant plates and grocery store shelves. Of course, visitors can take those eggs home or bring them to the on-farm restaurant, Clay, where a chef will use them to prepare breakfast. 

A few centuries of industrialization, urbanization, and globalization have collected people into cities, but the attraction of the countryside has always remained. In the new urban-centered world, enterprising farmers have found plenty of opportunities to sell their rural lifestyle along with their crops. Italy promoted the modern model for combining agriculture and tourism in the wake of World War Ⅱ, when the national government encouraged rural populations to continue producing food rather than move to urban areas in search of more profitable jobs. 

Agritourism acts as an umbrella term for a wide variety of activities that take place on farms, including farmstays, where guests sleep on-site. For varying investments of time, energy, and money, anyone can engage in our farming system, giving consumers a peek behind the farm-to-table world.