Your New Year's plan to move more is one of the toughest to stick to, and a group of scientists working with obese(过度肥胖的) mice think they're starting to understand why

    Rather than our sedentary(久坐的) lives causing weight gain, says Alexxai Kraviz, the National Institutes of Health neuroscientist who led the study, changes in brain chemistry after we start gaining weight affect our capacity to move.

    “Obses mice can move just fine,” says Kravitz, who published the work with his team in Cell Metabolism “They just don't.”

    What Kravitz's team found is that the activity of a particular dopamine(多巴胺) receptor linked to movement goes down as mice gain weight on a high-fat diet. So the nice slow down and they move less. And when the researchers restored the activity of that dopamine receptor—DR2—the mice started moving more, even though they were still obese. The team also saw that lean mice missing the DR2 receptor acted like obese mice. This is the target, says Kravitz—restoring that dopamine receptor function. “Maybe 20 or 30 years down the road, we could do that in people,” he says.

    And there is one more thing: The scientists fed normal mice and the mice lacking DR2 the same high-fat diet. Both sets of mice gained weight at the same rate.

    Kravitz says this is important because mice lacking DR2 move less from the get-go, whereas a normal mouse takes a little time to start seeing that dopamine receptor-related loss of exercise. The ability to exercise seems to be disconnected from weight gain, he says.

    “Exercise is a healthy thing to do, but its impact on weight loss has been exaggerated,” he says. “We have to be realistic about the size of the effect of exercise on weight, as opposed to health benefits.”

    Still, before you abandon your New Year's exercise plan, keep in mind that this study was done using a high-fat diet, and not the normal calorie restriction that people maintain when they diet.

    That's a big drawback to the work, says Vicki Vieira-Potter, a University of Missouri physiologist not involved in the study.

    “They feed the mice with high-fat diet, it damages the receptor, and that decreases activity. Those who plan to lost weight should remember high-fat diet is a nice way to cause obesity in the lab, but it's not the same as the normal situation of obesity,” she says.

    Sine also says that a lot of the weight gain in the mice came after they stopped moving around, which indicates that the loss of movement did impact obesity.

    Most drinks stating that they are fruit­flavored (水果味道的) contain no fruit at all, while most of the rest contain only a small quantity of fruit, according to a study carried by the British Food Commission.

    “Shoppers need to check the labels (标签) before buying drinks, though sometimes the actual content can be non­existent，” said Food Commission spokesperson Ian Tokelove. “Food production is highly competitive. {#blank#}1{#/blank#} It will increase profits, and consumers won't always realize they are being tricked.”

    Flavorings are focused on the flavors of natural food products such as fruits, meats and vegetables, or creating flavor for food products that do not have the desired flavors. Researchers analyzed the contents of 28 strawberry­flavored products sold in stores. {#blank#}2{#/blank#} Of the 11 products that did contain strawberries, five of them contained less than one percent real fruit. In addition, each juice box contained nearly eight teaspoons of sugar.

    {#blank#}3{#/blank#} Let's take jam as an example. Some strawberry­flavored jam was labeled as containing no artificial colors, flavors, or sweeteners, but it contained absolutely no strawberries at all.

    {#blank#}4{#/blank#} Consumers have the rights to know clearly about what they have bought. Under current UK law, food packages do not have to distinguish between natural and artificial flavoring. “Describing a product as strawberry flavor and covering the surface of the packet with pictures of strawberries is misleading. {#blank#}5{#/blank#} Unfortunately, it is also legal and widespread,” Tokelove said. “It's time to take measures to protect the consumers' rights.”

A. The products which contain real fruit are popular with people.

B. Even products advertised as more natural often contained no fruit.

C. They found that about 60 percent of them didn't contain any fruit at all.

D. If companies can cut their costs by using flavoring, they are likely to do so.

E. It is important and necessary to demand a small amount of flavoring in the products.

F. Actually the product contains just a tiny percentage of strawberry or even no fruit at all.

G. The Food Commission suggested all flavors used in a product should be listed on the packaging.

    Today marks the one-year anniversary of my father's death.Looking back at the past year,I cannot describe how hard it has been for me mentally and physically.

    For a long time I suffered in silence.I felt as if I was running in circles（圆圈）.I kept my tears to my sleep and my loneliness in my bedroom.

After my father's death,I began channeling all that pain into dance.But as a fairly new dancer,I haven't had too much stage experience.I recently performed at my school's winter concert for one of my classmates who is dealing with a rare illness.I dedicated（献上）the dance to her and my father.I only had one week.I was so anxious that I felt like I was having a heart attack.

    Luckily,my best friends came to my aid.What they said to me was one of the kindest things anyone has ever said.I will never forget what one of them said:"You are so beautiful because of your heart and beautiful mind.You have more kindness than some will ever have.I saw how much that dance meant to you,especially how it connected with your memories.It made me cry,that is how incredible you are."

Just surround yourself with people like my friend who will never think little of you.I am so proud of how much I've achieved and I know I will keep going,just as my father would have wished.

What Will Be Done-With All This Denim?

    All the denim (牛仔布) will be donated to Cotton From Blue to Green, which recycles jeans into UltraTouch Natural Cotton Fiber Insulation (纤维隔热材料), which is used to help build houses in places that have been damaged by hurricanes and other natural disasters. Your jeans will help keep clothes out of landfills (垃圾场), and build houses for families to live in! UltraTouch is made of 85% recycled fibers and is an environmentally safe, natural cotton fiber insulation.

It's a Fact

    It takes about 500 pairs of jeans to recycle enough denim to insulate one average-size U.S house.

Here's How You Can Get Involved!

1). Get a parent's permission and select as many denim jeans as you like. (Any denim clothing is OK)

2). The denim must be used.

3). The denim can be any brand.

4). The denim can be any color or size but must have been worn by a human (no doll clothes!).

5). Jeans must be received by June 30, 2017.

    By donating denim, you can give it a “new life” by converting it into UltraTouch Natural Cotton Fiber Insulation. Click here for more information about the denim drive.

    UltraTouch is composed of 85% recycled fibers and is an environmentally safe, non- itch natural cotton fiber insulation. For more information about UltraTouch, click here.

    A business executive（主管）was deep in debt and could see no way out. He sat on the park bench, head in hands, wondering if anything could save his company.

    Suddenly an old man appeared. “I can see that something is troubling you,” he said. After listening to the executive's words, the old man said, “I believe I can help you.” He asked the man his name, wrote out a check, and pushed it into his hand saying, “Take this money. Meet me here exactly one year from today, and you can pay me back at that time.” Then he turned and disappeared as quickly as he had come.

    The executive saw a check for $ 500,000, signed by John D. Rockefeller, then one of the richest men in the world! “I can settle all my debts immediately!” he realized. But instead, the executive decided to put the uncashed check in his safe. Just knowing it was there would give him the strength to work out a way to save his business, he thought.

    With renewed optimism, he made better deals and extended terms of payment. Within a few months, he was out of debt and making money once again. Exactly one year later, he returned to the park with the uncashed check. At the agreed-upon time, the old man appeared. But just as he was about to hand back the check and share his success story, a nurse came running up and grabbed the old man.

    “I'm so glad I caught him!” she cried.” hope he hasn't been bothering you. He's always escaping from the rest home and telling people he's John D. Rockefeller.” And she led the old man away. The astonished executive just stood there.

    Suddenly, he realized that it wasn't the money, real or imagined, that had turned him around. It was his newly found self-confidence that gave him the power to achieve anything he went after.

Riding School:

    You can start horse-riding at any age. Choose private or group lessons any weekday. There are 10 kilometers of tracks and paths for leisurely rides across farmland and open country. You will need a riding hat.

    Opening Hours: Monday through Friday: 9:00 a.m.-8:30 p.m. (3:30 p.m. on Saturdays)

    Phone: (412)396-6754 Fax:(412)396-6752

Sailing Club:

   Our Young Sailor's Course leads to the Stage 1 Sailing qualification. You will learn how to sail safely and the course also covers sailing theory and first aid. Have fun with other course members afterwards in the clubroom. There are 10 weekly two-hour lessons.

    Opening Hours: Tuesdays: 6:00 p.m.-8:00 p.m.

    Phone:(412)396-6644    Fax:(412)396-6644

Diving Centre:

    Our experienced instructors offer one-month courses in deep-sea diving for beginners. There are two evening lessons a week, in which you learn to breathe underwater and use the equipment safely. You only need swimming costume and a towel. Reduced rates for couples.

    Opening Hours: Monday and Friday: 6:30 p.m.-8:30 p.m.

    Phone:(412)396-6312    Fax:(412)396-6706

Medical Center:

    The staff of the Medical Center aim to provide convenient and comprehensive medical care to students and staff of the university. The center is well equipped and the staff here are trained to deal with a broad range of medical problems. Both female and male doctors as well as nursing staff are available for consultation. Also, all kinds of medicines are sold here and are cheaper for students than other drugstores.

    Opening Hours: 24 hours from Monday to Sunday

    Phone:(412)396-6649    Fax:(412)396-6648

Water sports Club:

    We use a two-kilometer length of river for speedboat racing, and water-skiing. A beginners' course consists of ten 20-minute lessons. You will learn to handle boats safely and confidently, but must be able to swim. The club is in a convenient central position and is open daily from 9 a.m. to 4 p.m., with lessons all through the day.

    Opening Hours: Monday through Friday: 9:00 a.m.-4:00 p.m.

    Phone:(412)396-6899    Fax:(412)396-6890