阅读理解
China became the first country to clone a
monkey using non-reproductive cells, reducing the need to keep lab monkeys and
paving the way for more accurate, effective, and affordable animal tests for
new drugs.
By December of 2017, Chinese
scientists had created two clone macaques named "Zhong Zhong" and
"Hua Hua" by nuclear transferring of somatic cells -- any cell in the
organism other than reproductive cells. This was the similar technology used to
create the famous clone sheep Dolly in 1996.
Tetra, a rhesus monkey born in
1999, is the world's first ever-cloned monkey, but it was done using a simpler
method called embryo splitting, but it could only generate four cloned
offspring at a time and cannot be genetically modified to suit experimental
needs, said Pu Muming, an academician at the Chinese Academy of Sciences and
the director of Institute of Neuroscience, CAS. "Cloning a monkey using
somatic cells has been a world-class challenge because it is a primate(灵长类)that
shares its genetic makeup, therefore all of its complexity, with humans."
Pu Muming said.
"For drug and other lab
tests, scientists have to purchase monkeys from all over the world, which is
costly, bad for the environment and produces inaccurate results because each
monkey might have different genes," Pu said. "By cloning monkeys
using somatic cells, we can mass produce large numbers of genetically same
offspring in a short time, and even change their genes to suit our needs,"
he added. "This can save time, cut down experiment costs, and produce more
accurate results, leading to more effective medicine."
Sun Qiang, director of the
non-human primate research facility at the institute, said most of the drug
trials are currently done on lab mice. However, drugs that work on mice might
not work or even have severe side effects on humans because the two species are
so different. "Monkeys and Humans are both primates, so they are much
closely related and testing on Monkeys is supposed to be as effective as
testing on humans," he said. This is especially useful in testing drugs
for neural diseases such as Parkinson's disease, metabolic and immune system
disease, and tumor, he added. "This achievement will help China lead the
world research in an international science project related to neural(神经的)mapping
of primate brains,"he said. However, bio labs from the United States,
Japan, and European countries are also very able, and they will quickly catch
up to China after the monkey cloning technology is made public, Sun
added." This means we have to innovate continuously and work extra harder
this year to stay ahead," he said.