Humans have launched themselves into the outer space. They've landed on the moon. They've built habitable space stations that orbit the Earth. The next giant leap for mankind is to reach another planet – specifically, Mars.

    The problem is that it's no easy task. The planet is 586 times further away from the Earth than the moon, and it'll take around 180 to 220 days to reach Mars, depending on where each planet is in its orbit. Such long periods in space have suggested many potential health problems, including hormonal changes, skin conditions, and muscle and bone deterioration (损耗).

    Here's where some furry friends come in. A wide range of animals have been in space, from fruit flies and spiders to cats, and dogs. Such experiments began as far back as the late 1940s in first tests to see if living things could withstand the extreme g-force (重力) of a rocket launch.

    Mice continue to play a very important part in space experiments, mainly because the animals make excellent test subjects. They're small, which makes them inexpensive and easy to care for. In addition, their size and short life span make it possible to do the equivalent of several human years of tests in a much shorter time. Finally, because mice are mammals, they share many common characteristics with humans in terms of genetics, biology and behavior.

    Astromice have hit the headlines recently, as a team of scientists led by Betty Nusgens, professor of biology at the University of Liege in Belgium, found that the mice suffered a 15 percent thinning of their skin after 91 days aboard the International Space Station (ISS).

    This experiment was part of a wider NASA mission (任务) called the Mice Drawer System (MDS). The Italian Space Agency developed the facility, which allows six mice to be housed, monitored, and automatically fed and watered aboard the ISS, among which three survived during the mission.

    The mice have participated in 20 separate experiments, to study such effects as osteoporosis (骨质疏松症), anemia (贫血) and heart health.

    Results for the 20 experiments are coming in gradually. But it's clear that mice continue to play an important role in the ongoing quest to conquer the final frontier.

    Nowadays it is common that people are buying more products and services than ever before through the Internet, so do Americans. And experts say the popularity of online sales is likely to spread to other countries. Online sales now represent as much as 10% of all retail sales in the United States. This has led traditional stores to seek new ways to keep their customers loyal.

Taking Lynne for example, she made good use of the Internet. She used the Internet to buy everything she needed for her Wedding and holiday gifts for her husband and daughter. Other than food, 90% of her purchases were made on her home computer. "I find that, by being able to go online, choose the things that I need, and have them delivered to me right at my doorstep, I eliminate all the driving, all the crowds, all the noise of that, and I usually get a better selection."

    There are a lot of people like her. Experts say American online shopping hit records in both November and December.57% of Americans have bought something electronically. Store owners worry that this growing amount of online sales will hurt their business. Cornell University marketing professor Ed Melaughlin says they can keep their customers by selling goods like clothing, which buyers may want to see and try on before purchasing. The stores could also offer things that are difficult to ship. Besides, some stores can please customers by offering to repair electronic products.

Bill Martin is the founder of Shopper Trak. His business helps stores learn about their customers. He said, "There is still a lot of emotion in the buying decision, you know, that takes place. Often you need that last sense of "Boy, this is exactly what I want before you are ready to part with money, and you can't always get that online. It's a rather cold process."

    While e-commerce worries some business owners, the only worry for delivery services is keeping up with the number of packages. UPS manager Dana Kline says her company is very busy at this time of the year.

    UPS is so busy that it has filled 55,000 temporary work positions during the holiday season.

    Mark Twain was a great writer. He was from the USA. He was born in 1835. He was also a famous speaker. He was famous for his sense of humor. Many people liked to listen to him talk because he liked to tell some interesting stories to make people laugh all the time.

    One day Mark Twain was going to a small town because of his writing. Before he was going to leave, one of his friends said to him that there were always a lot of mosquitoes in the town and told him that he'd better not go there. Mark Twain waved (摇动) his hand and said, ＂It doesn't matter. The mosquitoes are not relatives of mine. I don't think they will come to visit me.＂

    After he arrived at the town, Mark Twain stayed in a small hotel near the station. He went into his room, but when he was just about to have a rest, quite a few mosquitoes flew about him. The waiters felt very sorry about that. ＂I'm very sorry, Mr. Mark Twain. There are too many mosquitoes in our town.＂ One of them said to him.

    Mark Twain, however, made a joke, saying to the waiter, ＂The mosquitoes are very clever. They know my room number. They didn't come into the wrong room.＂ What he said made all the people present laugh heartily.

    But that night Mark Twain slept well. Do you know why? That was because all the waiters in the hotel were driving the mosquitoes away for him during the whole night.

    Buying new clothes isn't an easy matter for everyone, here are some tips(建议) for you .When you want to go shopping, decide how much money you can spend on new clothes. Think about the kind of clothes you really need. Then look for those clothes you really need. Then look for those clothes on sale.

    There are labels(标签) inside all new clothes. The labels tell you how to take care of your clothes. The label for a shirt may tell you to wash it in warm water. A sweater label may tell you to wash in cold water. The label on a coat may say "dry clean only", for washing may ruin this coat. If you do as the directions(说明)on the label, you can keep your clothes looking their best for a long time.

    Many clothes today must be dry cleaned. Dry cleaning is expensive. When buying new clothes, check to see if they will need to be dry cleaned. You will save money if you buy clothes that can be washed.

    You can save money if you buy clothes that are well-made. Well-made clothes last longer. They look good even after they have been washed many times. Clothes that cost more money are not necessarily better made. They do not always fit better. Sometimes less expensive clothes look and fit better than more expensive clothes.

    For as long as we've known about it, humans have searched for a cure for cancer. Across the world, countless amounts of time and money have been spent on researching a way to stop this terrible disease. But now, it seems like the answer could have been inside our own bodies the whole time.

    Recently, the Food and Drug Administration (FDA) in the US, a government agency that's responsible for healthcare, approved a new form of gene therapy (疗法) that could mean the end of a certain type of cancer.

    The therapy allows scientists to "train" the immune (有免疫力的) cells of sick patients to fight leukemia (白血病)—a form of blood cancer that mostly affects young people.

    The exciting new treatment works by removing healthy immune cells from the patient, known as T-cells, which are then changed to be able to "hunt down" cancer cells.

    The cells are then put back into the patient before they begin to get rid of the patient's leukemia over time, similar to how the body fights off other illnesses.

    "This is truly an exciting new day for cancer patients," Louis J. DeGennaro, president of the Leukemia and Lymphoma Society, said in a news release.

    Up until now, a long and painful marrow transplant (骨髓移植) was the only option for many leukemia patients.

    In this procedure, healthy blood cells are taken from a donator and placed into the sick patient, who also has to go through chemotherapy (化疗) to allow their body to adjust to the new cells.

    But with a recovery rate of around 83%—according to a news release published by the FDA—it's hoped that the days of painful trips to the hospital, or even death, are over for leukemia sufferers.

    "We're entering a new frontier in medical innovation (创新) with the ability to reprogram a patient's own cells to attack a deadly cancer," FDA representative Scott Gottlieb said in the release. "New technologies such as gene and cell therapies hold the potential to transform medicine and our ability to treat and even cure many incurable illnesses."

Ecobee3 Smarter WiFi Thermostat

    Smart thermostats have become the face of smart home technology for most, but depending on what your home is like, it's possible to say the ecobee3 is superior.

    Most of the smart thermostats carry the same benefits, including the ecobee3. They can learn your preferences and schedules, and then adjust the temperature accordingly. They're better-looking and more enjoyable to use than the basic pieces of plastic that occupy most households. Their very presence will probably make you more conscious about saving energy. And once you're able to heat up or cool down your house from your phone, without having to get out of bed, you won't want to go back.

    If you live in a larger household, the ecobee3 can be much more convenient—provided you pick up a couple more remote sensors. Yes, it gets pretty expensive at that point, but having those gives you effective control over the temperature in different rooms around your house. In comparison, other thermostats' measurements are largely limited to the area in which they' re installed (安装).

    If you live in a smaller place, that's no big deal; the ecobee3 still has distinct advantages. It is touch-enabled and more spacious, making it less annoying when you want to enter a WiFi password, see weather information, and so on. Still, all the smart thermostats are pretty great. Which one is best just depends on whether you need a whole-home solution or a more straightforward one. For now, if it's the former, go with the ecobee3.

    Ecobee3 Smarter WiFi Thermostat with Remote Sensor, available at all shopping websites.