Life-Changing Science Discoveries

    Here's a look at some discoveries that have changed the world. It's impossible to rank their importance, so they're listed in the order they were discovered

Micro-organism

    Before French chemist Louis Pasteur began experimenting with bacteria in the 1860s, people did not know what caused disease. He not only discovered that disease came from micro-organisms, but also realized that bacteria could be killed by heat and disinfectant(消毒剂). This idea caused doctors to wash their hands and disinfect their instruments, which has saved millions of lives.

Penicillin

    Antibiotics are powerful drugs that kill dangerous bacteria in our bodies that make us sick. In 1928, British Alexander Fleming discovered the first antibiotic, penicillin, which he grew in his lab. Without antibiotics, infections like strep throat could be deadly

DNA

    On February 28, 1853, James Watson of the United States and Francis Crick of England made one of the greatest scientific discoveries in history. The two scientists found the structure of DNA. Our genes are made of DNA and determine how things like what color hair and eye we'll have. In 1962, they were awarded the Nobel Prize for this work . The discovery has helped doctors understand diseases and may someday prevent some illnesses like heart disease and cancer.

X-rays

    Wilhelm Roentgen, a German physicist, discovered X-rays in 1895. X-rays go right through some substances, like flesh and wood, but are stopped by others, such as bones and lead. This allows them to be used to see broken bones or explosives inside suitcases, which makes them useful for doctors and security officers. For this discovery, Roentgen was awarded the first-ever Nobel Prize in Physics in 1901.

    Judge Frank Caprio is a famous person in the city of Providence, Rhode Island. And, he is starting to get noticed around the world, too. He is an 80-year-old judge in the capital city of Rhode Island, the smallest state in the U. S.. One of his jobs is to take charge of traffic court. That involves talking to people who have gotten traffic tickets for going though red lights or parking illegally. They go to traffic court to question the tickets. Caprio hears what they have to say. Then, he decides whether or not the ticket is legal.

Caprio recently heard the case of a young man who was driving his mother's car. He went through a light after it turned red. After he spoke with the high school student, Caprio decided to let him off with a warning—if he promised to go to college and graduate.

    Another video from the Providence traffic court came out earlier this week. It showed a woman speaking with Judge Caprio about a parking ticket. She went to traffic court after getting a ticket for parking in an area that only permitted parking after 10 a. m. . The ticket was written at 9:59 a. m. . The woman said the clock in her car showed 10 a. m., so she thought it would be OK. After some conversation, the judge decided to dismiss the ticket.

    But Caprio did tell her, “You violated the city laws.” He held up a large book of rules. He smiled and the woman laughed. He said: “Our parking enforcement officers are second to none in the country!” After talking with the court officer, he said “I think 9:59 is close enough. Matter is dismissed.”

    The video was viewed over 1 million times in just two days. One person wrote of the video: “This is so cute. What a great judge. LOVE THIS.” Others wondered if the video was real, because it seemed so funny. But, there actually are judges out there like Frank Caprio. He is as real as they come.

    In this Pennsylvania city, Pittsburgh is shrinking but getting wealthier. Since 2000, its population has declined by 95,000 while its income per capita (人均) has shot up 24 percent. The trend is taking hold in many other cities, like Buffalo in New York, Providence in Rhode Island and New Orleans.

    Some of these areas have created more high-paying jobs in energy, health care or education. Others have managed to reshape their manufacturing (制造业) for a new economy. Higher-paying jobs have a greater effect because they create demand for additional services. “The story in Pittsburgh is very positive, and other areas are looking at it as an example of the transformation that might be possible,” said Guhan Venkatu, who wrote an economic history of the area called “Rust and Renewal” for the Federal Reserve Bank of Cleveland.

    Carnegie Mellon University and the University of Pittsburgh have helped bring tech jobs and innovation (革新) to the area by sponsoring tech centers that help graduates start companies without moving to Silicon Valley or San Francisco. This has helped keep Pittsburgh's educated young population growing even as the entire population in the city has dropped.

    Pittsburgh has more STEM (science, technology, engineering and math) jobs than other shrinking cities, about 80,000 or 7% of all jobs. STEM jobs add productivity and income growth to the area. Manufacturers of high-tech medical equipment in the Pittsburgh area also have doubled employment in the last 10 years.

    However, some experts question whether growing income per capita can really make up for a declining population. According to Patrick Adler, a researcher at the University of Toronto, population loss does matter if it means lower-skilled workers have fled because of a lack of opportunity. What's more, high-paying jobs in education and health care can disappear if the population declines too greatly. So it'd be wise to find ways to increase the population.

    Why elephants rarely get cancer is a mystery that has confused scientists for decades. A study was led by researchers at Huntsman Cancer Institute (HCI) at the University of Utah and Arizona State University, including researchers from the Ringling Bros. Center for Elephant Conservation may have found the answer. According to the results, elephants have 38 additional modified copies of a gene (基因) that encodes p53, a well-defined tumor (肿瘤) suppressor, as compared to humans, who have only two. Further, elephants may have a more powerful mechanism for killing damaged cells that are at risk for becoming cancerous. In isolated elephant cells, this activity is doubled compared to healthy human cells, and five times that of cells from patients with Li-Fraumeni Syndrome, who have only one working copy of p53 and more than a 90 percent lifetime cancer risk in children and adults. The results suggest extra p53 could explain elephants' increased resistance to cancer.

    "Nature has already figured out how to prevent cancer. It's up to us to learn how different animals overcome the problem so we can adapt those strategies to prevent cancer in people," says co-senior author Joshua Schiffman, M.D., pediatric oncologist (肿瘤学家) at Huntsman Cancer Institute, University of Utah School of Medicine, and Primary Children's Hospital.

    According to Schiffman, elephants have long been considered a walking problem. Because they have 100 times as many cells as people, they should be 100 times more likely to have a cell slip into a cancerous state and cause the disease over their long life span of 50 to 70 years. And yet it's believed that elephants get cancer less often, a theory confirmed in this study. Analysis of a large database of elephant deaths estimates a cancer death rate of less than 5 percent compared to 11 to 25 percent in people.

    Alice Robb is an American science journalist who has written for the Washington Post and the New Republic. Her new book, Why We Dream, encourages us to rethink the importance of dreams and to become dream interpreters ourselves.

    Reporter: Recently there's been a massive interest in the science of sleep. Sleep plays a role in maintaining our mental health. Are dreams part of that process?

    Alice Robb: Dreams play a big role in helping us cope with stress, grief and psychological problems. Dreams are an opportunity to work through things that frighten us in real life, to play out worst-case situations in an environment where they have no consequences.

    Reporter: Has anyone explained why dreams contain such surreal (超现实的) elements, strange pictures of time, people, geography and so on?

    Alice Robb：When we dream, the logic centres of our brain—the frontal lobes (大脑额叶) —go dark, and chemicals associated with self-control, like serotonin (血清素) and norepinephrine (去甲肾 上腺素) , drop. At the same time, the emotion centres light up：we have a perfect chemical canvas for dramatic, psychologically intense visions.

    Reporter：You say neglecting to consider our dreams is like "throwing away a gift from our brains without bothering to open it. " What is the gift?

    Alice Robb: When we're dreaming, we're thinking in a state we never have access to by day. Dreams offer the opportunity to think in a different way and show new answers to problems. They show us blind spots on things we might be neglecting in our personal lives.