More than loo genes are related with increased risk of developing schizophrenia（精神分裂症）,bipolar disorder （躁郁症）and alcoholism（酗酒）,confirms a large study published in the recent issue of the British scientific journal Nature.

    The world's largest study into the genetic basis of mental illnesses was led by researchers from British universities,including University College London (UCL),Cardiff University and King's College London (KCL).

    Researchers believe that they are now much closer than before to understanding the complex biological causes, which make some people being at high risk of developing mental illnesses.They also believe that these findings could lead to new treatments.

    The researchers analyzed the DNA of about 37,000 patients with schizophrenia,bipolar disorder or alcoholism, and compared the smallest genetic changes to those found in about 113,000 healthy people.They then identified about 128 independent genetic variants（变体）at 108 locations on the human chromosomes（染色体）that contribute significantly to developing schizophrenia—83 of these sites have never before been linked to the illness,according to scientists.

    For example,people with the variant of the GRM3 gene,thought to be important in brain signaling,are around 2 to 3 times more likely to develop schizophrenia or alcohol dependence.The variant,which is found in approximately one in every 200 people,is also associated with a three times risk of developing bipolar disorder.

    "We could be looking at the next big drug target for treating mental illness,"Professor David Curtis from UCL, co-author of the paper,said."The work opens up new ways to prevent and treat mental illnesses by revealing the mechanisms involved in their development."

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    Although computers used to be large, expensive and difficult to use, they have been made smaller, cheaper and easier to use. As a result, more people have been buying computers for their homes and businesses. They are used to record information and make difficult things easy.

    Let's look at some of the many ways computers may affect(影响) your life.

    Want to get the best treatment at hospitals? Your doctors at hospitals have been greatly helped by computers to get information about patients. It is possible for doctors from different hospitals to read the records of patients, discuss them and make decisions on the best treatment. It would, at one time, take them hours and days to do so.

    Want to talk to your friends both at home and abroad? Then it's necessary to connect your computer to the Internet and set up your own e-mail letter box. You can then collect and send mails in seconds. It will be a waste of time and money to post your letters.

    Want to get advice from Michael Jordan on how to play basketball like a NBA super star? Now it is possible to find out what it is on the Internet.

    But if you think you have entered the information age because you have the chance to use the Internet, you are wrong. The reason is quite a simple one: over 98 percent of the information on the Internet is in English. The information on-line won't be helpful to you unless you can use English freely.

    My husband David was waiting at the door when our daughter Laura and I pulled in the driveway. It wasn't like him to be home so early. The disbelief on his face told me that something was up.

    "Do you still have a job?"

    "No. Redundant," he answered, looking away from me.

    "OK. We'll figure it out," I replied calmly.

    I actually had no idea how we were going to figure it out. I immediately started to think of how we'd cut costs and who we should start to get in touch with. That night, after David had fallen asleep, I cried myself to sleep, and frequently sobbed in the shower in the days that followed.

    I knew the loss of David's income would have great effect on us. He had worked for the same insurance company for twenty-one years and was our main income. I work at home caring for Laura, and my freelance(自由职业者的)income is uncertain. We have debts, and job hunting takes time.

    Still, I was more concerned about my husband's emotional state than our financial situation. David's sense of identity was tied to his job. He called his parents to tell them about losing his job, but didn't say a word to anyone else for weeks. He told me that he felt like "a failure".

It was tough for me to watch David struggle with unemployment. One night a couple of weeks after he lost his job, David woke me just before midnight, sweating, pacing the bedroom floor and saying he felt funny. We spent the night in the emergency room waiting to see if he had a heart attack. Thankfully, it was just a serious anxiety attack. It was then that I knew I needed to do more to understand what my husband was going through. Here is what I learned from my own experience—and from talking to experts—on how to support your spouse through a job loss.

    Garden of the Drunken Bai Pond

    With a history of more than 300 years, the Pond of the Drunken Bai, a classical garden in the style of Ming Dynasty, is among the Five Classical Gardens in Shanghai. "Bai" is said to be Li Bai, a famous poet in the Tang Dynasty. However, some believe that "Bai" indicates Bai Juyi, another well-known poet in the Tang Dynasty.

    Zhujiajiao Ancient Town

    Located at the bank of the Dianshan Lake in Qingpu District, Zhujiajiao Ancient Town, with a history of over 1,000 years, has been known as "Venice of Shanghai" for its simple but attractive appearance. Inside the own are rivers and bridges, giving tourists a sense of the ancient time.

    Upside-down House

    In China, the upside-down house is a new thing, but in foreign countries, it is getting more and more popular in recent years, especially in Poland. As is name suggests, the house is built inverted（倒置的）. Inside it, all the furniture and household items are placed upside down. People will feel the magic of a disorder space when walking in the house.

    Chenshan Botanical Garden

    The garden covers a total area of about 206 hectares（公顷）. Its theme is "plant and Health", combining research, education and landscape appreciation. It opened to the public in April, 2010, and is expected to be the largest one in Shanghai.

Tickets: 40 yuan per person; children under l.2m: free of charge if accompanied by an adult.

    Can you imagine a world without music？Studies show that public schools across the country are cutting back on music classes to save money. Worse, some schools have never had music classes to begin with. But without them, students' academic growth and emotional health could suffer. In fact, music classes are necessary for all students in schools.

    Recent studies by Brown University have shown that students who received music education classes were better in math and reading skills than those without music classes. Another study by The College Board found that students taking music and art classes got higher points. Students' academic success seems to depend on their taking part in music education.

    Music programs in public schools also help to add to a student's sense of pride and self-confidence. Teens today have too many learning tasks. Besides, they have family problems, self-confidence problems, relationship troubles, and choices about drugs and alcohol. All of these can stop academic success, but music education can help. A study by The Texas Commission on Drug and Alcohol Abuse found that students who took part in school music programs were less likely to turn to drugs. Music programs encourage students to work together to produce an excellent performance.

    Music crosses language, class, cultural and political boundaries (界限). Music allows students from different countries to connect. For example, at a school talent show, a new Japanese student played a piano duet (二重奏) with an American classmate. Although they could not communicate verbally (口头上), they were able to read the music in order to play the duet. Two students from different cultures worked as a team with self-confidence and common purpose through music.

    The gift of music is priceless. We need to be sure to have necessary music classes for all students. The world is losing its music, and putting music into schools is the first step to get it back.

Livestreaming (直播) through platforms such as Amazon Live and TikTok is an increasingly popular way to sell goods online. It usually lasts between 5 and 10 minutes, and someone promotes a product. Viewers can then readily buy it by just clicking on a link.

We analyzed (分析) 99, 451 sales cases on a livestream selling platform and matched them with actual sales cases. In terms of time, that is equal to over 2 million 30-second television advertisements.

To determine the emotional (情绪的) expression of the salesperson (销售员), we used two deep learning models: a face model and an emotion model. The face model discovers the presence or absence of a face in a frame of a video stream. The emotion model then determines the probability that a face is exhibiting any of the six basic human emotions: happiness, sadness, surprise, anger, fear or disgust. For example, smiling signals a high probability of happiness, while an off-putting expression usually points toward anger.

We wanted to see the effect of emotions expressed at different times in the sales cases so we counted probabilities for each emotion for all 62 million frames in our database. We then combined these probabilities with other possible aspects (方面) that might drive sales — such as price and product characteristics — to judge the effect of emotion.

We found that, perhaps unsurprisingly, when salespeople show more negative emotions — such as anger and disgust — the volume of sales went down. But we also found that a similar thing happened when the salespeople show high levels of positive emotions, such as happiness or surprise.

A likely explanation, based on our research, is that smiling can be disgusting because it lacks true feelings and can reduce trust in the seller. A seller's happiness may be taken as a sign that the seller is gaining interests at the customer's expense.