More than loo genes are related with increased risk of developing schizophrenia（精神分裂症）,bipolar disorder （躁郁症）and alcoholism（酗酒）,confirms a large study published in the recent issue of the British scientific journal Nature.

    The world's largest study into the genetic basis of mental illnesses was led by researchers from British universities,including University College London (UCL),Cardiff University and King's College London (KCL).

    Researchers believe that they are now much closer than before to understanding the complex biological causes, which make some people being at high risk of developing mental illnesses.They also believe that these findings could lead to new treatments.

    The researchers analyzed the DNA of about 37,000 patients with schizophrenia,bipolar disorder or alcoholism, and compared the smallest genetic changes to those found in about 113,000 healthy people.They then identified about 128 independent genetic variants（变体）at 108 locations on the human chromosomes（染色体）that contribute significantly to developing schizophrenia—83 of these sites have never before been linked to the illness,according to scientists.

    For example,people with the variant of the GRM3 gene,thought to be important in brain signaling,are around 2 to 3 times more likely to develop schizophrenia or alcohol dependence.The variant,which is found in approximately one in every 200 people,is also associated with a three times risk of developing bipolar disorder.

    "We could be looking at the next big drug target for treating mental illness,"Professor David Curtis from UCL, co-author of the paper,said."The work opens up new ways to prevent and treat mental illnesses by revealing the mechanisms involved in their development."

    When Shakespeare was twenty-one, he went to London, a very interesting place, to try his fortune.

    There was the famous London Bridge and St. Paul's Cathedral, and palaces and markets and long streets full of shops.

    Then, too, there were the daily crowds where could be seen people from all over the world. Knights, scholars and the highwayman (拦路强盗）or thieves, who had been infamous for their clever robberies, passed by each other.

    Here, also, were noblemen dressed in gold, from Italy and Spain and France; slaves from Spanish America, sea captains and ministers, soldiers and servants—all held by chances or interests within the gray walls which circled London, and whose gates gave welcome to as strange a crowd as could be found in the world.

    Into this curious crowd came Shakespeare, quick to see and eager to learn. And before long all these strange sights were as familiar to him as the faces of his own town's residents. Each one told its story to him so plainly that, as before he had learned the secrets of the fields and woods, so now he learned men and men's interests that make up the great world.

    And he learned these lessons so well that when he came to write his plays, he made such use of them as no writer ever made before or since; for it is the use of this knowledge of the world, combined with his own genius, that makes Shakespeare the greatest dramatist that has ever lived.

    If Confucius (孔子) were still alive today and could celebrate his September 28 birthday with a big cake, there would be a lot of candles. He'd need a fan or a strong wind to help him put them out.

    While many people in China will remember Confucius on his special day, few people in the United States will give him a passing thought. It's nothing personal. Most Americans don't even remember the birthdays of their own national heroes.

    But this doesn't mean that Americans don't care about Confucius. In many ways he has become a bridge that foreigners must cross if they want to reach a deeper understanding of China.

    In the past two decades, the Chinese studies programs have gained huge popularity in Western universities. More recently, the Chinese government has set up Confucius Institutes in more than 80 countries. These schools teach both Chinese language and culture. The main courses of Chinese culture usually included Chinese art, history and philosophy (哲学). Some social scientists suggest that Westerners should take advantage of the ancient Chinese wisdom to make up for the drawbacks of Westerners philosophy. Students in the United States, at the same time, are racing to learn Chinese. So they will be ready for life in a world where China is an equal power with the United States. Businessmen who hope to make money in China are reading books about Confucius to understand their Chinese customers.

    So the old thinker's ideas are still alive and well.

    Today China attracts the West more than ever, and it will need more teachers to introduce Confucius and Chinese culture to the West.

    As for the old thinker, he will not soon be forgotten by people in the West, even if his birthday is.

    When athletes at the 2020 Tokyo Olympics collect their medals, they'll not only be wearing something that celebrates their sporting performance, but something that symbolizes lastingness. For both the 2020 Olympics and Paralympics, organizers aim to make all of the gold, silver, and bronze medals out of used electronics. This strong message about how to make use of e-waste has gotten a lot of Japan involved.

    Starting in April 2017, the Japanese Olympic Committee began collecting old laptops, digital cameras, smartphones, and other abandoned electronics. The initiative(倡议)has achieved great  success. Already, the quantity needed for bronze medals has been met, and they're in the homestretch for silver and gold medals, meaning the collection process can pack up at the end of March.

    When looking just at the number of cell phones collected, the amount of waste is shocking. In a period of about 18 months, a little over 5 million smartphones were collected thanks to cooperation with NTT DOCOMO.

Japan's largest mobile phone operator allowed the public to turn in phones at their shops, which counted a lot in the project's success.

    After being taken apart and sorted, the small electronics underwent a smelting process to extract(提炼)all the gold, silver, and bronze elements. Thanks to this initiative, the worldwide struggle with e-waste will have a global platform. According to a study published by the United Nations University—44.7 million metric tons of e-waste were made in 2016. Only 20% of that was actually recycled. Unfortunately, this figure is set to rise significantly in the coming years, moving to 52.2 million metric tons by 2021. So while the Tokyo Olympics initiative might be just a drop in the bucket, it's a good start in showing what the public can do if they're made more aware of the issue.

    There is a popular belief among parents that schools are no longer interested in spelling. No school I have ever taught in has ever ignored spelling or considered it unimportant as a basic skill. There are, however, different ideas about how to teach it, or how much priority (优先) it must be given over general language development and writing ability. The problem is how to encourage a child to express himself freely and confidently in writing without holding him back with the complexities (复杂性) of spelling. That's why teachers often encourage the early use of dictionaries and pay attention to content (内容) rather than spelling.

    If spelling becomes the only focus of his teacher's interest, clearly a bright child will be likely to "play safe". He will tend to write only words within his spelling range, choosing to avoid adventurous language.

    I was once shocked to read on the bottom of a piece of writing about a personal experience. "This work is terrible! There are far too many spelling mistakes and your writing is terrible." It may have been a sharp comment on the pupil's spelling in writing, but it was also a sad sign that the teacher had failed to read the composition, which contained some beautiful expressions of the child's deep feelings. The teacher was not wrong to draw attention to the mistakes, but if his priorities had centered on the child's ideas, an expression of his disappointment with the spelling would have given the pupil more encouragement to seek improvement.

    It is quite reasonable to blame traffic jams, the cost of gas and the great speed of modern life, but manners on the road are becoming horrible. Everybody knows that the nicest men would become fierce tigers behind the wheel. It is all right to have a tiger in a cage, but to have one in the driver's seat is another matter altogether.

    Road politeness is not only good manners, but good sense too. It takes the most cool-headed drivers great patience to give up the desire to beat back when forced to face rude driving. On the other hand, a little politeness goes a long way towards reducing the possibility of quarrelling and fighting. A friendly nod or a wave of thanks in answer to an act of politeness helps to create an atmosphere of good will and calm so necessary in modern traffic condition. But such behaviors of politeness are by no means enough. Many drivers nowadays don't even seem able to recognize politeness when they see it.

    However, misplaced politeness can also be dangerous. Typical examples are the driver who waves a child crossing the street at a wrong place into the path of oncoming cars that may be not able to stop in time. The same goes for encouraging old ladies to cross the road wherever and whenever they want to. It always amazes me that the highways are not covered with the dead bodies of these grannies (奶奶).

    An experienced driver, whose manners are faultless, told me it would help if drivers learnt to correctly join in traffic stream without causing total blockages that give rise to unpleasant feelings. Unfortunately, modern drivers can't even learn to drive. Years ago, experts warned us that the fast increase of the car ownership would demand more give-and-take from all road users. It is high time for all of us to take this message to heart.