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题型:阅读理解 题类:常考题 难易度:普通

江苏省连云港市2018-2019学年高二上学期英语期末考试试卷

阅读理解

    Drug companies have spent billions of dollars searching for therapies to reverse or significantly slow Alzheimer's disease, but in vain. Some researchers argue that the best way to make progress is to create better animal models for research, and several teams are now developing mice that more closely imitate how the disease destroys people's brains.

    The US National Institutes of Health (NIH), the UK Dementia Research Institute and Jackson Laboratory (JAX) - one of the world's biggest suppliers of lab mice - are among the groups trying to genetically design more suitable mice. Scientists are also exploring the complex web of mutations(突变) that influences neurological (神经学的) decline in mice and people.

    "We appreciate that the models we had were insufficient. I think it's sort of at a critical moment right now." says Bruce Lamb, a neuro-scientist at Indiana University ~ho directs the NIH-funded programme.

    Alzheimer's is marked by cognitive impairment(认知损伤) and the build-up of amyloid-protein plaques (淀粉样蛋白块) in the brains of people, but the disease does not occur naturally in mice. Scientists get around this by studying mice that have been genetically modified to produce high levels of human amyloid protein. These mice develop plaques in their brains, but they still do not display the memory problems seen in people.

    Many experimental drugs that have successfully removed plaques from mouse brains have not lessened the symptoms of Alzheimer's disease in people. One focused stumble came last month, when three companies reported that their Alzheimer's drugs had failed in large, late-stage clinical trials. Although the drugs successfully blocked the accumulation of amyloid protein in mice, they seemed to worsen cognitive decline and brain shrinkage in people.

    The drive for better mouse models comes as genomics studies are linking the most common form of Alzheimer's to dozens of different genes. This diversity suggests that each case of the disease is caused by a different combination of genetic and environmental factors. "There is no single Alzheimer's disease," says Gareth Howell, a neuro-scientist at Jackson Laboratory (JAX) in Bar Harbor, Maine.

    Howell argues that scientists' reliance on lab mice with only a few genetically engineered mutations might have limited research. His own work suggests that in mice, just as in people, genetic diversity plays a part in determining how Alzheimer's develops.

(1)、What do you know about the lab mice used for the Alzheimer's research from the text?
A、The lab mice also display the memory problems. B、Suitable lab mice are fundamental to the research. C、Mice with Alzheimer's disease suffer from mutations. D、Drugs have been invented to slow Alzheimer's disease.
(2)、From paragraph 5, we can know that the experimental drugs"__________.
A、functioned well in large, early-stage clinical trials B、fail to make people get rid of the relevant symptoms C、successfully prevent people forming amyloid protein D、worsen cognitive decline and brain shrinkage in mice
(3)、What does Gareth Howell think of Alzheimer's?
A、It is various genes that count in the development of Alzheimer's. B、The increasingly polluted environment contributes to Alzheimer's. C、The most common form of Alzheimer's is the drive for better mice. D、It is caused by the accumulation of amyloid-protein plaques in people.
(4)、Which of the following could be the best title for the passage?
A、Experimental drugs successfully reverse Alzheimer's B、The real causes of Alzheimer's have been confirmed C、Alzheimer's is the biggest memory killer in the aged D、Frustrated Alzheimer's researchers seek better lab mice
举一反三
阅读理解

    Sydney has a huge bus system(系统). No buses accept cash, and a ticket needs to be bought ahead of time. The buses often run at busy hours and regularly(有规律地) during the day. The Sydney Explorer bus provides air-conditioned service and stops at 27 tourist attractions. Its partner, the Bondi Explorer, stops at 19 attractions. Tickets allow holders to jump on and off as they please, and they are valid(有效的) for one or two days. It's an easy way to see the city and the surroundings.

    Sydney's train service runs throughout the central city area and the surroundings. Tickets can be bought from machines that operate 24 hours a day or from ticket offices. The monorail(单轨铁路) travels through central Sydney. It is the most excellent way to gain a good view of the whole city. The monorail runs every three to five minutes, and it takes 15 minutes to complete its journey.

    Sydney is built around a harbor, and the Parramatta River has a large ferry(渡轮)system. It serves the area around the harbor. These include Taronga Zoo, Darling Harbor, Rose Bay, the North Shore, Cockatoo Island and Sydney Olympic Park. The ferries have operated for more than 135 years and 14 million passengers take the ferries each year.

    Water taxis can transport passengers to specific locations(地点), and offer guided tours of waterways. They also offer special services that some visitors may enjoy. The tickets sell for 20 AUD (Australian dollars)for a day or 57 AUD for a week. It is strange, isn't it?

阅读理解

    After the examination, the doctor told my parents my sight would get worse and that I would lose my sight finally. On the way home from hospital, no one said a word. One day, would I only imagine the scenery beyond the glass rather than see it?

    That September, I entered middle school. Most nights I had homework that included an armful of books to read. To keep up with other children, I took great trouble to finish the task. With my nose a couple of inches from the page, I was tired easily. What's worse, after I had read several pages on my own, the words slipped off the page into inky pools.

    However, then I did not have audio books and electric devices like kids do now. Instead, Mum volunteered to read out loud. Mum worked part-time, cleaned the house, cooked and spent time with Grandma. In spite of being so busy, she showed up in my room like clockwork. She put on her reading glasses. Mum always thought those glasses made her look old. To me, she looked like a teacher.

    In my room, Mum's voice raced with the ticking of the clock. Being forced to focus on listening, I found a way to keep my marks up and compete with the other kids. When the teacher asked a question, I raised my hand with confidence. Teachers praised me for having a good memory. Reading removed my fear for my failing sight, reading also made me curious about other people's challenges and how they managed. Though I could not use my eyes to fix on each passage, my mind lit up with every new book.

    True to what the doctor said, the worst came, but thanks to Mum, my sense of hearing now allows me to “see”. This was the most precious gift from a mother to her child.

阅读理解

    After the examination, the doctor told my parents my sight would get worse and that I would lose my sight finally. On the way home from hospital, no one said a word. One day, would I only imagine the scenery beyond the glass rather than see it?

    That September, I entered middle school. Most nights I had homework that included an armful of books to read. To keep up with other children, I took great trouble to finish the task. With my nose a couple of inches from the page, I was tired easily. What's worse, after I had read several pages on my own, the words slipped off the page into inky pools.

    However, then I did not have audio books and electronic devices like kids do now. Instead, Mom volunteered to read out loud. Mom worked part time, cleaned the house, cooked and spent time with Grandma. In spite of being so busy, she showed up in my room like clockwork. She put on her reading glasses. Mom always thought those glasses made her look old. To me, she looked like a teacher.

    In my room, Mom's voice compared with the ticking of the clock. Being forced to focus on listening, I found a way to keep my marks up and compete with the other kids. When the teacher asked a question, I raised my hand with confidence. Teachers praised me for having a good memory. Reading removed my fear for my failing sight, reading also made me curious about other people's challenges and how they managed. Though I could not use my eyes to fix on each passage, my mind lit up with every new book.

    True to what the doctor said, the worst came, but thanks to Mom, my sense of hearing now allows me to “see”. This was the most precious gift from a mother to her child.

阅读理解

    If you're planning on travelling, there are a few simple rules about how to make life easier both before and after your journey.

    First of all, always check and double­check departure (起程) time. It is amazing how few people really do this carefully. Once I arrived at the airport a few minutes after ten. My secretary had got the ticket for me and I thought she had said that the plane left at 10:50. When I arrived at the airport, the clerk at the departure desk told me that my flight was closed. Therefore, I had to wait three hours for the next one and missed an important meeting.

    The second rule is to remember that even in this age of credit cards, it is still important to have at least a little of the local currency (货币) with you when you arrive in a country. This can be necessary if you are flying to a place few tourists normally visit. Once I arrived at a place at midnight and the bank at the airport was closed. The only way to get to my hotel was by taxi and because I had no dollars, I offered to pay in pounds instead. "Listen! I only take real money!" the driver said angrily. Luckily I was able to borrow a few dollars from a clerk at the hotel, but it was embarrassing.

    The third and last rule is to find out as much as you can about the weather at your destination before you leave. I feel sorry for some of my workmates who travel in heavy suits and raincoats in May, when it is still fairly cool in London or Manchester, to places like Athens, Rome or Madrid, where it is already beginning to get quite warm during the day.

阅读理解

    Demand for the Chinese tech company's devices(设备) is red hot even though the country's overall market for smartphones is getting smaller Huawei's China sales rocketed more than 20% in the final quarter of 2018, and experts say that's partly due to the US govenment's global campaign against the company.

    "The latest tension between the US and China raised the patriotism(爱国主义) in Chinese consumers, said Jusy Hong, an analyst at research firm IHS Markit

    He pointed out that some Chinese companies encouraged employees to buy Huawei phones late last year. The moves were a gesture of support after the firm's chief financial officer was arrested in Canada in early December at the request of the United States.

    Huawei's booming sales show how major parts of its business continue to increase even as the United States tries to persuade other countries to shut Huawei products out of 5G wireless networks and pursues(追究) criminal charges against it. The company expects to overtake Samsung as the world's biggest smartphone maker by next year.

    Huawei sold 30 million phones in China in the last three months of 2018, nearly three times as many as Apple(AAPL), according to data published this week by research firms Canalys and IDC. Apple's sales plunged almost 20%.

    Huawei's success in China, the world's largest smartphone market, is more than about geopolitics(地缘政治). Chinese consumers love its flagship, high -end- phones because they have great cameras, cutting edge technology and cost less than the latest iPhones, according to analysts. And by offering a selection of cheaper phones, Huawei is able to target a bigger market.

    It also benefited from the troubles this year at ZTE (ZTCOF), a rival Chinese smartphone and telecommunications equipment maker. ZTE was banned by the US government from buying vital American parts for months last year.

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