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题型:阅读理解 题类:常考题 难易度:普通

江苏省连云港市2018-2019学年高二上学期英语期末考试试卷

阅读理解

    Drug companies have spent billions of dollars searching for therapies to reverse or significantly slow Alzheimer's disease, but in vain. Some researchers argue that the best way to make progress is to create better animal models for research, and several teams are now developing mice that more closely imitate how the disease destroys people's brains.

    The US National Institutes of Health (NIH), the UK Dementia Research Institute and Jackson Laboratory (JAX) - one of the world's biggest suppliers of lab mice - are among the groups trying to genetically design more suitable mice. Scientists are also exploring the complex web of mutations(突变) that influences neurological (神经学的) decline in mice and people.

    "We appreciate that the models we had were insufficient. I think it's sort of at a critical moment right now." says Bruce Lamb, a neuro-scientist at Indiana University ~ho directs the NIH-funded programme.

    Alzheimer's is marked by cognitive impairment(认知损伤) and the build-up of amyloid-protein plaques (淀粉样蛋白块) in the brains of people, but the disease does not occur naturally in mice. Scientists get around this by studying mice that have been genetically modified to produce high levels of human amyloid protein. These mice develop plaques in their brains, but they still do not display the memory problems seen in people.

    Many experimental drugs that have successfully removed plaques from mouse brains have not lessened the symptoms of Alzheimer's disease in people. One focused stumble came last month, when three companies reported that their Alzheimer's drugs had failed in large, late-stage clinical trials. Although the drugs successfully blocked the accumulation of amyloid protein in mice, they seemed to worsen cognitive decline and brain shrinkage in people.

    The drive for better mouse models comes as genomics studies are linking the most common form of Alzheimer's to dozens of different genes. This diversity suggests that each case of the disease is caused by a different combination of genetic and environmental factors. "There is no single Alzheimer's disease," says Gareth Howell, a neuro-scientist at Jackson Laboratory (JAX) in Bar Harbor, Maine.

    Howell argues that scientists' reliance on lab mice with only a few genetically engineered mutations might have limited research. His own work suggests that in mice, just as in people, genetic diversity plays a part in determining how Alzheimer's develops.

(1)、What do you know about the lab mice used for the Alzheimer's research from the text?
A、The lab mice also display the memory problems. B、Suitable lab mice are fundamental to the research. C、Mice with Alzheimer's disease suffer from mutations. D、Drugs have been invented to slow Alzheimer's disease.
(2)、From paragraph 5, we can know that the experimental drugs"__________.
A、functioned well in large, early-stage clinical trials B、fail to make people get rid of the relevant symptoms C、successfully prevent people forming amyloid protein D、worsen cognitive decline and brain shrinkage in mice
(3)、What does Gareth Howell think of Alzheimer's?
A、It is various genes that count in the development of Alzheimer's. B、The increasingly polluted environment contributes to Alzheimer's. C、The most common form of Alzheimer's is the drive for better mice. D、It is caused by the accumulation of amyloid-protein plaques in people.
(4)、Which of the following could be the best title for the passage?
A、Experimental drugs successfully reverse Alzheimer's B、The real causes of Alzheimer's have been confirmed C、Alzheimer's is the biggest memory killer in the aged D、Frustrated Alzheimer's researchers seek better lab mice
举一反三
阅读理解

    Sonya and her family have been homeless since she was 3 years old. Over the years, they have moved more than 15times to different shelters around New York City. Moving around was hard on Sonya。At school, Sonya hid her homeless from teachers and other students. She didn't want to be treated differently from other kids.

    In sixth grade, Sonya discovered a way to deal with some of her stress. She began studying dance at her middle school. “IT was a way for me to express myself, instead of just holding everything in,”she explains. Soon, Sonya auditioned(试演)for a summer dance camp run by Alvin Alley, a famous dance company. She was accepted. “I was excited,”says Sonya.

    Dancing became an even more important part of Sonya's life in high school. But things were not going well for Sonya at school. Each time her family moved to a new shelter, Sonya often took care of her younger sisters and brothers. She helped them get ready in the morning and took them to school. They would be on time, but Sonya would be late.

    Worrying about her family kept Sonya from thinking about her own future. That changed the summer after 11th grade. Sonya learned she would have to go to summer school to graduate. She became determined to succeed, no matter what. “It was a wake-up call,”she says.“I had to focus on school and on myself.”

    Sonya made up the work that she had missed, and finally graduated from high school. No one in her family had gone to college before. But in September 2015, Sonya enrolled in the State University of New York at Potsdam. She plans to become a doctor for kids and to teach dance to children who have disabilities.

阅读理解

    We talk about people being "colour-blind" but very few of us are. Even those who describe themselves as colour-blind are normally just colour lack. A strongly, colour-blind person will still be able to tell 20 different colours, compared to the 100 or so that normal-sighted people see.

    Pingelap, a tiny island in the Pacific, is a beautiful spot but one that has a' genetic trouble. It is known as Colour-blind Island because so many people who live on this remote island can only sec in black and white.

    Not being able to see in colour is bad enough. But one is lander, Herrol, who's a fisherman, also struggles in full sunlight because all he sees is a painful burnt-out image. "I find it difficult to go outside in the sun," he says, "because when it's sunny I cannot see to do my work."

    But if being truly colour-blind is rare, why is it that around 10% of the population of Pingelap live in a totally black and white world?

    Well,we know that in 1780 the population of Pingelap was all but wiped out by a tsunami (海啸). As few as 20 people survived, one of whom was the king. It's believed he had a genetic fault that causes colour-blindness and he passed this fault on to his many generations.

    There is one advantage. Herrol can see well, really well, in the dark. So when it gets dark, Herrol and his friends get in their boats and hunt flying fish. They hang up flaming torches and the fish are attracted to the flames. "This type of fishing is fun," Herrol says, "especially if we catch plenty. So even though it's hard work we enjoy it."

阅读理解

    As any plane passenger will confirm, a crying baby is almost impossible to ignore, no matter how hard you try. Now scientists believe they may have worked out why. A baby's cry pulls at the heartstrings(扣人心弦)in a way while other cries don't, researchers found.

    Researchers found that a baby's cry can trigger unique emotional responses in the brain, making it impossible for us to ignore them—whether we are parents or not. Other types of cries, including calls of animals in great pain, fail to get the same response, suggesting the brain is programmed to respond specifically to a baby's cry.

A team of Oxford University scientists scanned the brains of 28 men and women as they listened to a variety of calls and cries. After 100 milliseconds — roughly the time it takes to blink (眨眼) —two parts of the brain that respond to emotion lit up. Their response to a baby's cry was particularly strong. The response was seen in both men and women—even if they had no children.

    Researcher Dr Christine Parsons said, “You might read that men should just notice a baby and step over it and not see it, but it's not true. There is a special processing in men and women, which makes sense from an evolutionary(演化的)view that both men and women would be responding to these cries.” The study was in people who were not parents, yet they are all responding at 100ms to these particular cries, so this might be a fundamental response present in all of us regardless of parental status.

    Fellow researcher Katie Young said it may take a bit longer for someone to recognize their own child's cries because they need to do more “fine-grained analysis”. The team had previously found that our reactions speed up when we hear a baby crying. Adults performed better on computer games when they heard the sound of a baby crying than after they heard recordings of adults crying.

阅读理解

    As Amy Hagdorn rounded the corner across the hall from her classroom, she ran into a tall boy from the fifth grade running in the opposite direction.

    "Watch it. Squirt." the boy yelled, as he kept away from the little third grader. Then, with an unfriendly smile on his face, the boy took hold of his right leg and imitated the way Amy limped(跛行) when she walked.

    Amy closed her eyes for a moment.

    "Forget it!" she told herself as she headed for her classroom.

    It wasn't as if he were the only one. It seemed that ever since Amy started the third grade, someone teased her every single day. The tease made Amy feel all lonely.

    Back home at the dinner table that evening, Amy was quiet. Her mother knew that things were not going well at school. That's why Patti Hagdorn was happy to have some exciting news to share with her daughter

    "There's a Christmas Wish Contest on the newspaper, she announced." Write a letter to Santa and you might win a prize.

    Out came a pencil and a piece of paper and Amy went to work on her letter. She wrote:

Dear Santa Claus,

    My name is Amy. I am 9 years old. I have a problem at school. Can you help me, Santa? Kids laugh at me because of the way I walk and run and talk. I have cerebral palsy(脑瘫). I just want one day when no one laughs at me or makes fan of me.

Love

Amy

    The next day, a picture of Amy and her letter to Santa made the front page of the News Sentinel. The little girl's story spread quickly. She asked for such a simple, yet remarkable Christmas gift-just one day without being teased.

    During that unforgettable Christmas season, over two thousand people from all over the world sent Amy letters or cards of friendship and support.

    Amy did get her wish of a special day without being teased. Additionally, teachers and students in her school talked together about how bad tease can make others feel.

阅读理解

    It began as a game: High school and college students studying computer technology figured out they could use personal computers to break into telephone company computers and make free, long-distance telephone calls. These young computer talents soon gained the name "hackers".

    Police arrested a few hackers, but many went on to even more complex hacking. One of them was arrested for making illegal telephone calls and later he used a phone to change a police officer's credit records to get back at the officer for arresting him. He also used a computer to change his college records to give himself better grades.

    As hackers gained experience  they began invading computers at banks, airlines and other businesses. In one case a hacker instructed an airline's computer to give him free airplane tickets.

    The U.S. government is worried that hackers may break into its networks of defense computers. The government's secrets are easily attacked because thousands of government computers are connected by telephone lines that hackers can get into.

    In November 1988, a college student entered a U.S. Defense Department computer network called Arpanet. The hacker injected a computer program that made copies of itself throughout Arpanet. Some hackers use viruses to destroy all the data in a computer. But in this case, government officials shut down the network before the program reached every computer in the system. Shutting down the system angered many researchers who were using the computers. The hacker turned himself in to the police and he was charged with a crime.

    The incident put the spotlight on computer hacking in the United States. Many companies have hired experts to protect their computers from hackers, and many computer experts now advise companies on how to protect their computers.

    The U.S. government believes foreign governments have hired hackers to try to break into top-secret defense computers.

    Experts disagree over whether a computer network can ever be safe from hacking. But in the future, some of the most outstanding minds in the U.S. will be working to frustrate the attempts of computer hackers.

阅读理解

    Nasr Majid started hunting this fall at Blackwater National Wildlife Refuge (保护区)on the Eastern Shore of Maryland in USA, He's one of the relatively few new hunters who officials hope will help stop a nearly four-decade decline nationally in what has become a hobby for fewer than 5 percent of Americans.

    Natural resources and wildlife, officials in Maryland are encouraging hunting of deer, turkeys and some other wild animals, which is believed to be good for the environment. Without hunting, they say, sika deer will overpopulate the wildlife refuge and they'll overeat the bushes and other plants that provide important habitat for birds. On the western shore of the Chesapeake Bay, hunting is also important to prevent the spread of diseases such as Lyme.

    In many families, the hunting tradition has been handed down for generations^ But as longtime sportsmen age and children lose interest, the number of hunters in the United States fell by 2 million, from 2011 to 2018, to about 11 million.

    "Everything is changing. Kids are growing up in front of video games and computers instead of going hunting." said Chris Markin, a hunting specialist for the state natural resources department. "Adults usually focus on working and providing for their families. Those pressures are preventing many other potential hunters from going out, and from raising the next generation of hunters."

    To avoid such a decline, a new approach is needed. Government agencies and nonprofit groups are now launching mentoring (指导) programs to train more hunters, which not only helps preserve an industry and a culture but also means more protection for wildlife and their habitats through deer population control and investment.

    Luckily, there are those still eager to learn, like Majid. He was just looking for an outdoor hobby he could share with his children when he came across the mentors-hip program. Now, he feels capable of hunting on his own, but also has someone he can text with questions that pop up. His new pastime has already paid off for him—on his second hunt with his mentor, in the last minutes of daylight, he bagged his first deer.

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