"Over the years the unthinkable hasbecome thinkable and today we sense we are close to being able to alter humanheredity œ#)." These were the words of David Baltimore of the CaliforniaInstitute of Technology, on December 1st, when he opened a three-day meeting inWashington to discuss the morality and use of human gene editing. Dr Baltimoreis an old hand at these sorts of discussions, for he was also a participant inthe Asilomar conference, in 1975, which brought scientists together to discussa safe way of using the then-new tcchnology of recombinant DNA, and whoserecommendations influenced a generation of biotechnology researchers.

Four decades on, the need for a similarsort of chin-wag has arisen. The InternationalSummit on Human Gene Editing has been held by the national scientific academiesof three countries — America, Britain and China. They are particularlyconcerned about whether gene editing should be used to make heritable changesto the human germ line, something Dr Baltimore described as a deep andtroubling question. Like those of Asilomar, the conclusions of this meetingwill not be binding. But the hope is that, again like Asilomar, a mixture ofcommon sense and peer pressure will create a world in which scientists aretrusted to regulate themselves, rather than having politicians and civilservants do it for them. The meeting is being held against a backdrop of rapidscientific advance, Since 2012 research into a new, easy-to-use editing tool calledCRISPR-Cas9 has blossomed. This technique involves a piece of RNA (a chemicalmessenger, which can be used to recognise a target section of DNA) and anenzyme (酶)called a nuclease that can snip unwanted genes out and paste new ones in.

Public interest was aroused in April,when Chinese scientists announced they had edited genes in non-viable ( 无活力的) humanembryos, and again in November when British researchers said they hadsuccessfully treated a one-year-old girl who had leukaemia ( 白血病),using gene-edited T-cells. T-cells are part of the immune system that attack,among other things, tumour cells. The researchers altered T-cells from ahealthy donor to encourage them to recognise and kill the patient's cancer, tomake them immune to her leukaemia drug, and to ensure they did not attack herhealthy cells.

In another recent development, a firmcalled Edit as Medicine, which is based in Cambridge, Massachusetts, has saidit hopes, in 2017, to start human clinical trials of CRISPR-Cas9 as a treatmentfor a rare genetic form of blindness known as Leber congenital amaurosis (伯氏先天性黑蒙).Though other companies are already testing gene-editing therapies, these employolder, clunkier forms of the technology that seem likely to have lesscommercial potential. Moreover, researchers at the Broad Institute, also inCambridge, said this week that they had made changes to CRISPR-Cas9 whichgreatly reduce the rate of editing errors — one of the main obstacles to thetechnique's medical use.

On the subject of germ-line editing,Eric Lander, the Broad's head, told the meeting it would be useful only in rarecases and said it might be a good idea to "exercise caution? before makingpermanent changes to the gene pool. The need for caution is advice that mightalso be heeded by those pursuing work in animals other than people, and inplants — subjects not being covered by the summit.

    Recently actor Adrien Grenier has launched(发动)a campaign to reduce the amount of single-use plastic usage in order to protect and save marine (海洋的)wildlife and the environment. Plastic drinking straws are among many single-use plastic products contributing to the great loss of marine life, but they're a great place to start because they're something that are used by millions of Americans who are unaware that they're so damaging.

    Americans use more than 500 million straws daily, which is enough to fill 127 school buses each day and they can't be recycled. That means plastic straws might end up in oceans, where fish and other marine wildlife mistake the small bits for food and swallow them. After seeing a photo of a beached whale with a belly full of plastic, Grenier felt the inspiration to launch the Lonely Whale Foundation, hoping to inspire and educate others on the challenges faced by marine wildlife.

    Along with stopping the use of straws, Grenier hopes to educate consumer on the dangers of other single-use plastic items such as grocery bags and water bottles. While many Americans use these plastic products in their daily life, there are many alternatives that can help protect the environment such as straws made from stainless steel, glass, and even bamboo instead of plastic.

    In addition to quitting your straw habit, you can further help the environment by taking the I Choose to Reuse commitment, and stop your use of single-use coffee cups, checkout bags and bottled water. Instead, take advantage of any number of alternative reusable products.

    Need another reason to stop drinking from straws? Grenier also says using straws can cause wrinkles!

    Superfast double­decker (双层) trains will be taking passengers from London to six big cities in the UK by 2033. The first phase (阶段) linking London to the West Midlands with a connection to HS1 is expected to open in 2026, and the second  phase to Manchester and Leeds in 2032.

    The government set out a plan for the high­speed rail network in 2012. When the project is finished, it will take less time to get to London from major cities like Birmingham, Manchester and Leeds. Traveling at a speed of up to 250 mph, passengers will be able to come and go from Birmingham to London in 49 minutes, reducing the journey time by almost half from one hour and 24 minutes.

    A journey from Birmingham to Leeds will be reduced from two hours to 57 minutes and a journey from Manchester to London will be reduced from two hours and 8 minutes to one hour and 8 minutes.

    “HS2  is an  important  part of transport's  low­carbon future,” Transport  Secretary Justine Greening said. Some people aren't happy about the plan, though. HS2 will cost around ￡33 billion. It will also be built near some towns and villages, disturbing the people that live there.

    But the Chancellor of the Exchequer (财政大臣) George Osborne thinks it will help build the future for Britain. “It's a long­term decision，” he said.

    HS2 is designed for everything around the needs of the passengers. It will provide a new and exciting travel experience. There will be plenty of room, intelligent ticketing, a good service and high quality comfort and access to trains. This is a transport network for the new century and beyond.

    TransNatura International Nature Photo Competition

    The application is open, and all photographers are invited from all over the world, except the jury (评委会) and the organizers. The basic requirement is that the recordings have to be made of natural habitats without disturbing the wildlife. On the photos only wild animals can be included.

    Two categories:

    A Category: Open—any type of nature photography, representing animals, plants, landscape, and so on

    B Category: The art of flying—nature pictures that represent the movement of flying animals and the beauty of flying

    The assessment by the jury: 16th September〜10th October

    Announcement of results: 30th of October

    Exhibition Opening: 23th of November

    The works received will be evaluated and decided upon by an international jury made up of the five persons from Hungary and Romania.

    A total number of competition prizes will be awarded:

    Grand Prize—1,000 Euro;

    1st Prize—600 Euro;

    2nd Prize—400 Euro;

    3rd Prize—200 Euro.

    Entry requirements:

    A participant may enter the competition with at most four pictures per category.

    The pictures for the competition have to be submitted before 15th of September in the form of digital images, in jpg format.

    The participant must have full copyright over the submitted photos.

    The entry fee is 10 Euro for a category, 15 Euro for two categories.

    Additional information can be obtained by e-mail at: transnatura@vadon.ro.

    Getting older is a natural part of life. Changes as you get older are usually gradual. Certain physical changes are common. How fast your body can burn calories slows over time, which means that your body needs less food energy than before.

    How much and how well you sleep will likely change. Most people start needing reading glasses around forty, and many have some hearing loss later in life. Starting in your fifties, bone aging increase. How you feel as you get older depends on many things, including what health problems run in your family and the choices you make.

    If your family members have diseases or chronic (慢性的) health problems like high blood pressure, then you may have a greater chance of having those problems yourself. But it doesn't mean you will definitely have the same problems. Actually, the lifestyle choices you make can help reduce your chances of getting illness that run in your family. And even if you do get a family illness, choosing to be physically active, to eat healthy foods, and to learn how to deal with stress can keep the illness from destroying your ability to enjoy your golden years.

    What do you need to do to feel your best as you age? One of the most important things you can do for your health at any age is to be physically active. Physical activity keeps your body strong, and it helps with how you feel. People who stay active are less likely to get depressed.

    Your mental and emotional health is also important. Protect or improve your emotional health by staying in touch with friends, family, and the community. People who feel connected to others are more likely to feel happy than those who do not.

    Maybe ten-year-old Elizabeth put it best when she said to her father, "But, Dad, you can't be healthy if you're dead."

    Dad, in a hurry to get home before dark so he could go for a run, had forgotten to wear his safety belt－a mistake 75% of US population makes every day. The big question is why.

    There have been many myths about safety belt ever since their first appearance in cars some forty years ago. The following are three of the most common.

    Myth the Number One: It's best to be "thrown clear" of a serious accident.

    Truth: Sorry, but any accident serious enough to "throw you clear" is able to be serious enough to give you a very bad landing. And chances are you'll have traveled through a windshield(挡风玻璃) or door to do it. Studies show that chances of dying after a car accident are twenty－five times in cases where people are "thrown clear".

    Myth Number Two: Safety-belts "trap" people in cars that are burning or sinking in water.

    Truth: Sorry again, but studies show that people knocked unconscious(昏迷) due to not wearing safety belts have a greater chance of dying in these accidents. People wearing safety belts are usually protected to the point of having in these accidents. People wearing safety belts are usually protected to the point of having a clear head to free themselves from such dangerous situation, not to be trapped in them.

    Myth Number Three: Safety belts aren't needed at speeds of less than 30 miles per hour(mph).

    Truth: When two cars traveling at 30 mph hit each other, an unbelted driver would meet the windshield with a force equal to diving headfirst into the ground from a height of 10 metres.