Your New Year's plan to move more is one of the toughest to stick to, and a group of scientists working with obese(过度肥胖的) mice think they're starting to understand why

    Rather than our sedentary(久坐的) lives causing weight gain, says Alexxai Kraviz, the National Institutes of Health neuroscientist who led the study, changes in brain chemistry after we start gaining weight affect our capacity to move.

    “Obses mice can move just fine,” says Kravitz, who published the work with his team in Cell Metabolism “They just don't.”

    What Kravitz's team found is that the activity of a particular dopamine(多巴胺) receptor linked to movement goes down as mice gain weight on a high-fat diet. So the nice slow down and they move less. And when the researchers restored the activity of that dopamine receptor—DR2—the mice started moving more, even though they were still obese. The team also saw that lean mice missing the DR2 receptor acted like obese mice. This is the target, says Kravitz—restoring that dopamine receptor function. “Maybe 20 or 30 years down the road, we could do that in people,” he says.

    And there is one more thing: The scientists fed normal mice and the mice lacking DR2 the same high-fat diet. Both sets of mice gained weight at the same rate.

    Kravitz says this is important because mice lacking DR2 move less from the get-go, whereas a normal mouse takes a little time to start seeing that dopamine receptor-related loss of exercise. The ability to exercise seems to be disconnected from weight gain, he says.

    “Exercise is a healthy thing to do, but its impact on weight loss has been exaggerated,” he says. “We have to be realistic about the size of the effect of exercise on weight, as opposed to health benefits.”

    Still, before you abandon your New Year's exercise plan, keep in mind that this study was done using a high-fat diet, and not the normal calorie restriction that people maintain when they diet.

    That's a big drawback to the work, says Vicki Vieira-Potter, a University of Missouri physiologist not involved in the study.

    “They feed the mice with high-fat diet, it damages the receptor, and that decreases activity. Those who plan to lost weight should remember high-fat diet is a nice way to cause obesity in the lab, but it's not the same as the normal situation of obesity,” she says.

    Sine also says that a lot of the weight gain in the mice came after they stopped moving around, which indicates that the loss of movement did impact obesity.

    You may have heard of the American Dream, an ideal that has powered the hopes of Americans for generations.

    It began as a belief that the US was a land of opportunity, and that anyone could achieve success through hard work. At times, the dream has referred to home ownership, a good job, retirement security or each generation doing better than the last.

    Yet today, this concept seems to have greatly changed. As Time magazine pointed out, quite different from the older generation, many Millennials (the generation born after 1980) redefine(重新定义) the American Dream as “day-to-day control of your life”. They “prize job mobility, flexible schedules, any work that is more interesting than typing, and the ability to travel”, said the magazine.

    Home ownership, once the cornerstone of the American Dream, is becoming a smaller priority for this generation. Meanwhile, nearly 40% of them choose travel as part of their dream. And entrepreneurship(创业) is a rising favorite, as nearly 26% of Millennials consider self-employment as part of their dream.

    So what has led to this huge change?

    Many point fingers at the poor economy. “Modern young Americans seem bound to face a world stamped by ever narrowing opportunity and social stagnation(停滞),”noted The Daily Beast.

    “The rate of 16-to 24-year-olds out of school and out of work is unusually high at 15%. Many college graduates have taken jobs that don't require a degree,” Time reported.

    The magazine worries that these difficulties may lead to a lost generation who are “unable to ever truly find their feet on the corporation's ladder”.

    Dan Kadlec, a reporter of Time, sees Millennials as resetting their expectations.”This situation is different for young adults today,” he wrote. “A true American dream has to feel attainable, and many Millennias are feeling they can only attain a day-today lifestyle that suits them.”

    Many people believe that you lose the ability to learn new languages as you get older. Language experts, however, will tell you that you're never too old to learn a new language. As you get older, it can be more difficult to learn a new language, though.

    Children and adults learn new languages in different ways. For children, language is their life. They study for thousands of hours every year, because they need to learn languages to become part of their communities. Adults, on the other hand, are already part of a language community. Learning a new language means becoming part of another language community, and adults rarely get the chance to practice as much as young children do.

    Moreover, children learning a new language are expected to make mistakes. This gives them freedom when learning to be daring and confident. Adults, however, often feel pressured to be perfect when learning a new language. This can discourage many people and make it even harder to learn a new language.

    When young children learn a new language, they come to see various languages as a “normal” part of society. This mindset （思维模式） helps them embrace learning a new language without feeling like they're doing something unusual or “too hard”.

    So if you want to learn a new language, go for it! It's never too late to learn a new language. If you're older, it may take more work, but it can be done. If you're a young child, though, now is the time to step out and learn a new language!

    If you thought pilots dimmed（调暗）the lights before takeoff to give you some shuteye, think again. Believe it or not, the dim lighting could actually help save your life in case of a plane emergency.

    The dimmed lights before taking off the runway and landing are a flight precaution used to help passengers' eyes adjust quicker during an emergency escape. “Going from a brightly lit environment to one that's completely dark would require some time for our eyes to focus and see the escape slide,” Alice Theriault, service director for Air Canada wrote in a press statement. “Since we need to have all the seconds on our side in the event of an emergency, dimming the lights is one of many steps we take to ensure the safety of our customers.”

    The phenomenon that your eyes see those strange speckles (小斑点) as your sight adjusts to a dark place after being in a light place is called dark adaptation. It normally takes our eyes about 20 to 30 seconds to see best in a dark room. The brighter the lights, the longer it takes for our eyes to adjust, which is why dimming the plane lights could shorten your “dark adaptation” time since you haven't been sitting under fluorescent bulbs (荧光灯) all flight.

    Not only does dimming lights add valuable time to the escape process, but it reduces the tension on your eyes if you need to look outside, or see the emergency lighting along the passage. “It helps keep you in the right direction.” Patrick Smith, an airline pilot and author of Cockpit Confidential told The Telegraph. “It also makes it easier for flight attendants to assess any outside risks, such as fire or debris, that might affect an escape.” So next time a pilot dims the lights, just know it's for your safety, even though it creates a gentle atmosphere for your takeoff into the sky.

May's Midi Festival

    As a rock festival, the Midi Festival 2017 in Beijing presented a musical carnival for fans. It was the 13th year of the outdoor music feast. This year, about 100 rock bands from home and abroad performed on five stages. It was held at a suburban park known for its mountains and grasslands. With beautiful scenery and exciting music, it was a good opportunity to enjoy rock with friends and family.

    2：00—10：30 P. m. , from April 29 to May 1. China Music Valley Grassland Park, Pinggu District. 400-610-3721.

    Fans of Painting

Ancient Chinese calligraphers(书法家)and painters were fond of painting on the folds of fans. Their excellence has left a wealth of outstanding works. A fan painting show exhibited 990 Ming and Qing(1368—1911)dynasty calligraphy and painting works on folding fans. They were selected from the collection of the National Museum of China. The themes of these fan paintings fell into four categories：natural landscapes, flowers and birds, figures and calligraphy.

    10：00 a. m. —2：30 P. m. , from April 29 to May 29. National Museum of China, 16 East Chang'an Avenue. 010-651-6400.

    Poetic Portraits

    Two artists held a joint exhibition with paintings featuring portraits of Chinese women in poetic poses. Wang Xiaojin, who is from Shandong Province, has been exhibiting since 1993. The other artist, Xu Zhigang, is originally from Liaoning Province, but is now in Beijing.

    10：00 a. m. —8：00 P. m. , from April 28 to June 20. Rong Gallery, Sheraton Pudong Hotel, 38 Pujian Road, Pudong New Area. 0137-6408-7294.

    Group Show

    The artist group,“island6”, worked in new media and held a show titled     Body-City-Mechanism. Through interactive video, photography, oil on canvas and sculpture, the artists explore themes of man and cyberspace.

    10：00 a. m. —6：00 P. m. , from April 30 to June 28. Studio Rouge, 50, Moganshan Road, Putuo District. 021-5252-7856.

    A project in Gambia is empowering women and reducing dangerous waste at the same time.

    The Waste Innovation Center, funded by the European Union's Global Climate Change Alliance, shows women in the Brikama area how to recycle waste into useful materials and products, which they can then sell in local markets.

    Wood-like waste is recycled into charcoal (木炭), for example, which can be used to supersede firewood and reduce the number of trees that are cut down for firewood. Food waste is recycled into compost(混合肥料)to function as environmentally friendly fertilizers and plastic is turned into many useful things.

    Supported by Waste Aid UK and the Gambia Women's Initiative (GWI), among others, the project provides women with skills they can use to become self-sufficient (自给自足的). Women learning at the center come from five communities, and some of them travel as far as 12 miles to learn these important skills that will provide them with an income, according to The Guardian.

    Isatou Ceesay, who now leads the GWI, highlighted the need to focus on economic equality in her country, telling The Guardian, "In terms of education, women are the ones who are always behind. Boys are chosen to go to school. When we conduct our training, we find women can do a lot, but don't know who they are, or how to carry out things. "

    According to the World Health Organization's Country Cooperation Strategy 2018—2023 report, the main environmental issue facing Gambia is poor waste management in urban areas. Ndey Sireng Bakurin, executive director of the National Environment Agency, has voiced concern over health and environmental risks, such as water pollution, the increase of insects as well as flooding that occur as a result of poor waste management.