Guide to four of the most exciting new adventure trips for 2017:

    Sahara

    Attractions: International Expeditions   Length: 18 days   Price: $13,998

Details: Remember the movie Ishtar? Now you, too, can spend days wandering in the desert, just like warren Beatty and Dustin Hoffman. Designed for rugged travelers, the camping expedition crosses1,500 miles of Niger's Sahara in four—wheel—drive vehicles.

    Departure Time: May 12     Information: 800-633-4731;  ietravel.com

    Across Patagonia: From the Andes to the Ocean

    Attractions: Boundless Journeys   Length: 10 days    Price: $8,995

    Details: The newest route across Patagonia starts high in the Argentine Andes and follows the Futaleufu River into Chile all the way to the Pacific Ocean. Travelers start by trekking along the river, changing to rafts before taking up kayaks for the final leg.

    Departure Time: March 5    Information: 800-941-8010; boundless, com.

Tribal(部落的)India

    Attractions: Myths and Mountains      Length: 17 days        Price: $17,530

    Details: For the travelers who have already visited the best-known India sites, this new trip visits a relatively unexplored state in central India ruled by the Vindhyachal Range and known for its wildlife, waterfalls, ancient sites and tribal culture.

    Departure Time(出发时间): Feb 17   Information: 800-670-6984; myths.com

    Dalmatian Coast Biking

    Attractions: Backroads            Length: 7 days           Price: $7,298

    Details: The company's first foray into Croatia follow scenic roadways across four islands between Dubrovnik and Spht.

    Departure Time: May 7    Information: 800-462-2848; backroads.com

    Google previously announced successful tests of machine learning systems designed to assist doctors. In one case, Google reported AI had examined eye diseases with equal accuracy to doctors. Other tests showed that machine learning can be used to study large amounts of patient data to predict future medical events.

    Now the company has published two new studies showing a high level of success in identifying metastatic breast cancer. Metastatic means that cancer has spread from its main area to other parts of the body. Metastatic breast cancer is one of the deadliest, causing about 90 percent of all breast cancer deaths worldwide.

    In metastatic breast cancer patients, the cancer often travels to nearby lymph nodes（淋巴结）. Usually doctors examine lymph node tissue under a microscope to see whether cncer is present Google notes that previous studies have shown that up to one-fourth of metastatic lymph node classifications end up being changed after a second examination. In addition, studies show that small metastatic material can be missed up to 67 percent of the time when examinations happen under extreme time restrictions.

    Google says it created a mathematical algorithm(算法).The algorithm, called Lymph Node Assistant, is trained to find characteristics of tissue affected by metastatic cancer. When the system examined tissue images (图像), it was able to differentiate between metastatic cancer and non-cancer 99 percent of the time. In addition, the Lymph Node

    Assistant is highly effective at finding the positions of the cancers. Some of these positions would be too small for doctors themselves to identify. The research also showed that the algorithm method can reduce the usual time needed to examine the disease by about 50 percent.

    But Google makes clear the Al-based system is not meant to replace the work of medical professionals. Instead, it is designed to reduce the number of false identifications and help doctors work faster and more effectively.

    (The New York Times, Oct.7) The 2019 Nobel Prize in physiology(生理学) or medicine was jointly awarded to three scientists — William G. Kaelin Jr., Peter J. Ratcliffe and Gregg L. Semenza — for their work on how cells sense and adapt to oxygen availability. The Nobel Assembly announced the prize at the Karolinska Institute in Stockholm on Monday.

    Their work established the genetic mechanisms(机制) that allow cells to respond to changes in oxygen levels. The findings have implications(启示) for treating a variety of diseases.

    Why did they win?

    "Oxygen is the lifeblood of living organisms(生物体)," said Dr. George Daley, dean of Harvard Medical School. "Without oxygen, cells can't survive." But too much or too little oxygen can be deadly. The three researchers tried to answer this question: How do cells regulate their responses?

    The investigators uncovered detailed genetic responses to changing oxygen levels that allow cells in the bodies of humans and other animals to sense and respond to fluctuations(波动), increasing and decreasing how much oxygen they receive.

    Why is the work important?

    The discoveries reveal the cellular mechanisms that control such things as adaptation to high altitudes and how cancer cells manage to hijack(攫取) oxygen. Randall Johnson, a member of the Nobel Assembly, described the work as a "textbook discovery" and said it would be something students would start learning at the most basic levels of biology education.

    "This is a basic aspect of how a cell works, and I think from that standpoint alone it's a very exciting thing." Johnson said.

    The research also has implications for treating various diseases in which oxygen is in short supply — including anemia, heart attacks and strokes — as well as for treatment of cancers that are fed by and seek out oxygen.

Westwinds Farm Campsite

    Open April - September

    (Booking is advised for holidays in July and August to guarantee a place.)

    Jim and Meg Oaks welcome you to the campsite. We hope you will enjoy your stay here. We ask all campers to show due care and consideration whilst staying here and to observe the following camp rules.

    Keep the campsite clean and tidy: dispose of litter in the bins provided; leave the showers, toilets and washing area in the same state as you found them; ensure your site is clear of all litter when you leave it.

    Don't obstruct rights of way. Keep cars, bikes, etc. off the road.

    Let sleeping campers have some peace. Don't make any noise after 10 o'clock at night or before 7:30 in the morning.

    Dogs must be kept on a lead. Owners of dogs that disturb other campers by barking through the night will be asked to leave.

    Disorderly behavior will not be tolerated.

    The lighting of fires is strictly prohibited.

    Ball games are not allowed on the campsite. There is plenty of room for ball games in the park opposite the campsite.

    Radios, portable music equipment, etc. must not be played aloud.

    The management reserves the right to refuse admittance.

At school, I was in the top set for maths. My teachers recommended that I study economics and statistics as my A-level subjects, but I had my mind set on a life fulfilled by the arts.

In fact, I was a victim of a gender stereotype made stronger since birth, that men do science and maths and women do arts or languages. Computer science, technology and physics just did not figure in my teenage world view. Nobody popular in my school chose to study those subjects.

Reality struck hard when I began attending job interviews and interviewers would say: "It's great that you speak foreign languages, but what else do you do?" Nobody asked my friends who had studied science or technology those questions.

A survey recently showed that three of the best-paid jobs for women are in the technology sector. It's a sector that really can change the world. We must show girls that technology has an effect on every industry out there, from fashion to architecture to journalism. Anybody can learn to code and these days it's as important as reading and writing. I've realized that at university I'd achieved the wrong kind of literacy. Not being able to code limit your impact on the world far more than an ignorance of great literature.

Now I have a five-year-old daughter. I don't want her to blindly follow gender roles the way I did. I want her to know the fact that a science or technical degree will not limit her creativity but expand it and broaden her horizons far more than my arts background could. I'm exposing her to Minecraft and apps, which help improve analytical thinking and problem solving skills. I'm hoping that my daughter will discover and accept her potentials in science and want to change the world.

Central Axis: The Backbone of Beijing

Beijing Central Axis (中轴线), running north-south through the heart of the old city of Beijing and governing the overall layout of the capital, is{#blank#}1{#/blank#}integration of building complexes and archeological sites. Initially constructed in the 13th century and shaped in the 16th century, Beilng Central Axis was continuously perfected over seven centuries, giving rise to a well-organized and imposing building ensemble that manifests (彰显) the {#blank#}2{#/blank#}(idea) order of the ancient Chinese capital deep {#blank#}3{#/blank#}(root) in the capital planning tradition for over two millennia.

From Yongding Gate to the Bell and Drum Towers via Zhengyang Gate, Tian'anmen, Taihe Palace, Jingshan Mountain, Beijing Central Axis connects the outer, inner and imperial city {#blank#}4{#/blank#} the imperial palace. The main buildings along the central axis are symmetrical and staggered in {#blank#}5{#/blank#}(high), thus creating a unique and magnificent picture. In addition to {#blank#}6{#/blank#}(form) the backbone of the frame of Beijing city, it serves as the best embodiment of the capital's boundless charm {#blank#}7{#/blank#}makes it a famous historical and cultural city.

The Central Axis of Beijing which links the ancient times and the present has experienced the changes of times and witnessed the continuous development of the Chinese civilization. Nowadays, the application for the world heritage status of Beijing Central Axis {#blank#}8{#/blank#}(include) in the core area planning already, and this amazing urban landscape is becoming a development axis that {#blank#}9{#/blank#}(highlight) the protection of the ancient capital and the development of the city. In the future, it will continue to glow (焕发) with vibrant charm and nourish the Chinese civilization which stands in the East of the world with a {#blank#}10{#/blank#}(calm) and more confident posture.