题型:阅读理解 题类: 难易度:普通
人教版(2019) 选择性必修第三册 Unit 4 Adversity and Courage限时训练
"Given that signs of Alzheimer's disease (老年痴呆症) start to accumulate in the brain several decades before the disease begins, understanding the connection between sleep and cognition (认知) earlier in life is critical for understanding the role of sleep problems as a risk factor for the disease," said study author Yue Leng, PhD, of the University of California, San Francisco.
The study involved 526 people with an average age of 40. They were followed for 11 years. Researchers looked at participants' sleep duration and quality. Participants wore a wrist activity monitor for three continuous days on two occasions approximately one year apart to calculate their averages. Participants slept for an average of six hours. Participants also reported bedtime and wake-up time in a sleep diary and completed a sleep quality survey with scores ranging from 0 to 21. A total of 239 people reported poor sleep with a score greater than five.
Researchers also looked at sleep fragmentation (碎片化), a measure of restlessness during the sleep period expressed as a percentage. The higher the value, the more sleep is interrupted. Participants were divided into three groups based on their sleep fragmentation score. Of the 175 people with the most interrupted sleep, 44 had poor cognitive performance 10 years later, compared to 10 of the 176 people with the least interrupted sleep.
After adjusting for age, sex, race, and education, people who had the most interrupted sleep had more than twice the possibility of having poor cognitive performance when compared to those with the least interrupted sleep. There was no difference in cognitive performance at midlife for those in the middle group compared to the group with the least interrupted sleep.
However, due to the small sample size, the researchers were unable to fully investigate potential race or sex differences. "More research is needed to assess the link between sleep disturbances and cognition at different life stages and to identify if critical life periods exist when sleep is more strongly associated with cognition," Leng said.
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