More than loo genes are related with increased risk of developing schizophrenia（精神分裂症）,bipolar disorder （躁郁症）and alcoholism（酗酒）,confirms a large study published in the recent issue of the British scientific journal Nature.

    The world's largest study into the genetic basis of mental illnesses was led by researchers from British universities,including University College London (UCL),Cardiff University and King's College London (KCL).

    Researchers believe that they are now much closer than before to understanding the complex biological causes, which make some people being at high risk of developing mental illnesses.They also believe that these findings could lead to new treatments.

    The researchers analyzed the DNA of about 37,000 patients with schizophrenia,bipolar disorder or alcoholism, and compared the smallest genetic changes to those found in about 113,000 healthy people.They then identified about 128 independent genetic variants（变体）at 108 locations on the human chromosomes（染色体）that contribute significantly to developing schizophrenia—83 of these sites have never before been linked to the illness,according to scientists.

    For example,people with the variant of the GRM3 gene,thought to be important in brain signaling,are around 2 to 3 times more likely to develop schizophrenia or alcohol dependence.The variant,which is found in approximately one in every 200 people,is also associated with a three times risk of developing bipolar disorder.

    "We could be looking at the next big drug target for treating mental illness,"Professor David Curtis from UCL, co-author of the paper,said."The work opens up new ways to prevent and treat mental illnesses by revealing the mechanisms involved in their development."

    In addition to the official basketball world, various other types of basketball are practiced around the world.

    Wheelchair Basketball

    Wheelchair basketball was invented in 1946 by former American basketball players, who, after wartime injury, wanted once again to experience the excitement of a highly athletic sport within a team environment. It is now played in more than 80 countries by over 25,000 men, women and children with a physical disability which prevents them from playing competitive basketball on their feet.

    http://www.iwbf.org

    Beach Basketball

    Beach basketball is an exciting, non-stop action game played in the sand. The game was born more than forty years ago on the physical education fields of Gulf Shores School. This kind of basketball, invented by Philip Bryant, has grown from an extremely effective skill improvement game to a very popular, widespread competitive sport.

    http://www.beachbasketball.com

    Street Basketball

    Street Basketball or streetball is mainly played as a leisure game, but streetball players can also compete against each other. There are no specific streetball rules and the game is played outdoors; the players make up their own rules to play. Streetball is very popular among younger players and allows players to publicly show their own individual skills.

    http://www.streetball.com

    Deaf Basketball

    Basketball for the deaf (unable to hear in one or both ears) men and women has been played since the early 1920s. The game today has exactly the same rules as FIBA (International Basketball Federation).

    http://www.dibf.org

    Bankshot Basketball

    Bankshot is a new game of skill and challenge that is often described as “mini golf, but with a basketball.” Bankshot is the only sports system that allows the able-bodied and athletes with a disability to play together at the same time. This game is about no running, jumping, or body contact(接触)and relies on the shooting skill.

    http://www.bankshot.com

    You are given many opportunities in life to choose to be a victim or a creator. When you choose to be a victim, the world is a cold and difficult place. “They” did things to you which caused all of your pain and suffering. “They” are wrong and bad, and life is terrible as long as “they” are around. Or you may blame yourself for all your problems, thus internalizing(内化) your victimization. The truth is, your life is likely to stay that way as long as you feel a need to blame yourself or others.

    Those who choose to be creators look at life quite differently. They know there are individuals who might like to control their lives, but they don't let this get in the way. They know they have their weaknesses, yet they don't blame themselves when they fail. Whatever happens, they have choice in the matter. They believe their dance with each sacred(神圣的) moment of life is a gift and that storms are a natural part of life which can bring the rain needed for emotional and spiritual growth.

    Victims and creators live in the same physical world and deal with many of the same physical realities, yet their experience of life is worlds apart. Victims relish (沉溺) in anger, guilt, and other emotions that cause others—and even themselves—to feel like victims, too. Creators consciously choose love, inspiration, and other qualities which inspire not only themselves, but all around them. Both victims and creators always have choice to determine the direction of their lives.

    In reality, all of us play the victim or the creator at various points in our lives. One person, on losing a job or a special relationship, may feel as if it is the end of the world and sink into terrible suffering for months, years, or even a lifetime. Another with the same experience may choose to first experience the grief, then accept the loss and soon move on to be a powerful creative force in his life. In every moment and every circumstance, you can choose to have a fuller, richer life by setting a clear intention to transform the victim within, and by inviting into your life the powerful creator that you are.

    Many years later, when people recall the 2018 Russia World Cup, they will remember many things. With the tragic ending of the defending champion Germany, Mexico has triumphantly and suddenly lost three goals in the face of Sweden. But people will never forget the back of a lonely person. That is Lionel Messi.

    31-year-old Messi took off the green armband of his left arm and suddenly fell out. In the recent match, he and his team lost the game against France. The 19-year-old striker Mbappé relentlessly ripped apart the Argentine defense line and scored twice, which made a great contribution to the victory of France.

    On this planet, anyone who knows a little about football knows the name Lionel Messi and his golden years from 2007 to 2017.

    In 2007, 19-year-old Messi tied Real Madrid three times with a hat-trick, and began his legendary career.

    In the past ten years, Mr. Football, the Golden Globe Award and the Golden Boot Award have been taken over by him.

    He led Argentina and Barcelona to make a name for themselves in the world, and has a brilliant record in the Champions League, America's Cup and World Cup.

    Eleven years later, Messi stood on the Kazan Stadium. After four World Cups, he knew that this might be the last time he led Argentina to the World Cup.

    Since 1986, Argentina has never won a championship again. As a captain, he has a great responsibility, even stating that he would withdraw from the national team if he did not win the championship this year.

    This is a prophecy.

    Messi, who eventually failed to save the game, did not receive any interview after standing up on the lawn; leave behind only a legendary image for the world.

    First-time shoppers at Seattle-based Amazon Go may feel as though they were stealing. That's because the 1,800 square-foot grocery store, which opened its doors to the public on January 22, has no cashiers or even checkout counters. Instead, as the name indicates, customers merely grab what they need and go! But before you start celebrating, the goods are not free—the cost of the purchase(s) is/are calculated electronically using “Just Walk Out” technology.

    The process is simple. Upon entering the store, shoppers “sign-in” by scanning their smartphones. Every item selected gets added to the bill automatically. If the customer changes his mind, all he has to do is return the purchase to the shelf, and it will be removed from the final bill. Though consumers will not find everything they need, they will be able to buy basics like bread, milk, and drinks. There are also numerous ready-to-eat breakfast, lunch, and dinner choices made by chefs in the on-site kitchen. Those that prefer to cook at home can select from the wide variety of Amazon Meal Packages.

    Once the customer exits the store, the system processes the purchases and charges the cost to their Amazon account. Within seconds, the customer is notified of the deal with a digital receipt that lists each item bought, as well as the time spent in the store. The accurate tracking is possible thanks to multiple smart cameras that monitor everything the shopper is doing. Kumar explains,“Cameras figure out which interactions(互动) you have with the shelves. Computer vision figures out which items are taken. Machine-learning also determines which item it is.” The company insists that the system is so accurate that shoplifting(偷盗) is impossible. And they should know, considering that Amazon employees have been shopping there since 2015!

    The store has raised some concern about the jobs of the over 3.5 million cashiers in America. However, Amazon officials say they have nothing to worry about because human employees are not being displaced. They are simply assigned other essential tasks, like preparing meals, restocking shelves, assisting customers, and solving technical issues.

    Although toys packaging says it's educational, it doesn't make it so. That's the finding from a new study in JAMA Pediatrics that found some toys being marketed as language promoters got in the way of learning.

    Research shows that for kids to understand, speak and eventually read or write a language, they need to hear it - lots of it. And it's never too early for parents and to caregivers to get talking. That explains the booming industry in talking electronic toys that claim to help kids learn language.

    Professor Anna Sosa, of Northern Arizona University, led the study and says she gave families three different kinds of toys to play with: books, traditional toys like humble blocks and a shape sorter, and electronic toys. Sosa says she picked those toys because they are advertised in their packaging as language-promoters for babies between the ages of 10 and 16 months.

    "We had a talking on farm-animal names and things," Sosa says of the electronic toys. "We had a baby cell phone. And we had a baby laptop. So you open the cover and start pushing buttons, and it tells you things. The parent-child couples were asked to play separately with each type of toy over the course of three days."

    "When there's something else that's doing some talking, the parents seem to be sitting on the sidelines and letting the toy talk for them and respond for them," Sosa says. "That's bad because the best way a toy can promote language in infants and toddlers is by stimulating interaction between parent and child. There's simply no evidence that a young child can learn language directly from a toy. It isn't responsive enough. It isn't social."

    As for the other toys, traditional blocks and puzzles stimulated more conversation than the electronic toys, and books outscored them all. But don't underestimate the humble block. While traditional toys fell short of books in interaction quantity, Sosa notes, they kept pace in terms of quality.