Your New Year's plan to move more is one of the toughest to stick to, and a group of scientists working with obese(过度肥胖的) mice think they're starting to understand why

    Rather than our sedentary(久坐的) lives causing weight gain, says Alexxai Kraviz, the National Institutes of Health neuroscientist who led the study, changes in brain chemistry after we start gaining weight affect our capacity to move.

    “Obses mice can move just fine,” says Kravitz, who published the work with his team in Cell Metabolism “They just don't.”

    What Kravitz's team found is that the activity of a particular dopamine(多巴胺) receptor linked to movement goes down as mice gain weight on a high-fat diet. So the nice slow down and they move less. And when the researchers restored the activity of that dopamine receptor—DR2—the mice started moving more, even though they were still obese. The team also saw that lean mice missing the DR2 receptor acted like obese mice. This is the target, says Kravitz—restoring that dopamine receptor function. “Maybe 20 or 30 years down the road, we could do that in people,” he says.

    And there is one more thing: The scientists fed normal mice and the mice lacking DR2 the same high-fat diet. Both sets of mice gained weight at the same rate.

    Kravitz says this is important because mice lacking DR2 move less from the get-go, whereas a normal mouse takes a little time to start seeing that dopamine receptor-related loss of exercise. The ability to exercise seems to be disconnected from weight gain, he says.

    “Exercise is a healthy thing to do, but its impact on weight loss has been exaggerated,” he says. “We have to be realistic about the size of the effect of exercise on weight, as opposed to health benefits.”

    Still, before you abandon your New Year's exercise plan, keep in mind that this study was done using a high-fat diet, and not the normal calorie restriction that people maintain when they diet.

    That's a big drawback to the work, says Vicki Vieira-Potter, a University of Missouri physiologist not involved in the study.

    “They feed the mice with high-fat diet, it damages the receptor, and that decreases activity. Those who plan to lost weight should remember high-fat diet is a nice way to cause obesity in the lab, but it's not the same as the normal situation of obesity,” she says.

    Sine also says that a lot of the weight gain in the mice came after they stopped moving around, which indicates that the loss of movement did impact obesity.

    Trapped under six stories of ruins after the Haiti earthquake leveled his hotel, Dan Woolley believed he was going to die. But rather than give in to despair, the film-maker spent 65 hours beneath the earth looking up ways t treat his injuries on his iPhone. He also wrote a moving diary for his family, thinking they would only read his last message of love and comfort after his death. Instead, he was pulled from the disaster after a week-and will soon be reunited with his family.

    Mr. Woolley had travelled from America to Haiti with his colleague David Hames. Both had been working for charity. He was in the entrance-hall when the earthquake struck and just had time to dive into a comer before the building fell. Buried under tons of ruins, the film-maker downloaded a first aid application to his iPhone. He used the light from the iPhone to show him his injuries and diagnosed it properly as a broken leg. Then, he used the instructions from the app to treat the serious bleeding. The app advised him not to go to sleep if he felt he was going into shock. The resourceful Mr. Woolley set his phone alarm to go off every 20 minutes to keep him awake. New technology has played a huge part.

Mr. Woolley used a small black notebook to write messages to his family. He had thought his relatives would read them after he was dead. “I was in a big accident. Don't be upset at God,” he wrote, “I'm still praying that God will get me out, but He may not. But He will always take care of you.”

    Mr. Woolley was eventually located by a French rescue team and removed to the U.S. where he was reunited with his wife. Speaking after being flown to Miami for surgery, he said, “Boy, I cried. I wanted to use that time to do everything I could for my family. If it could be just to leave some notes that would help them in life, I would do that.”

He is now looking forward to seeing his family.

    What would you say if we told you that you could learn to speak a new language in only 7 days? Pretty unbelievable right? But how could it be? To find out,we spoke to David-one of our brave Babbel learners—to see how the Babbel app successfully got him speaking Norwegian(挪威语)in just one week.

How much time did you learn each day?

    I didn't need to give my entire life over to learning Norwegian. Each Babbel lesson takes only 15 minutes, and I set myself the achievable aim of finishing three Babbel lessons daily.This took only 45minutes each day.

How did the Babbel app help you learn so quickly?

    The Babbel app has a course plan for beginners that taught me how to make sentences in Norwegian within the first few days. Then I was able to personalize my learning by selecting single-topic lessons on eating, drinking, music, culture, traveling and so on. This allowed me to quickly enlarge my vocabulary!

    This way of learning kept me highly active,and made sure I wasn't bored to tears with grammar practice that we all remember from school!

    “After 7 days I was able to introduce myself in Norwegian,talk about my hobbies and interests, and most importantly,communicating with a native Norwegian speaker in a real conversation and I could even play a joke or two!”

    Would you introduce this app to others?

    Certainly! Babbel has 14 languages to choose from so if you're thinking about brushing up on your German for a business trip, or learning a bit of Portuguese (葡萄牙语) for next year's summer vacation, you'll be happy to hear that you only need an app, 7 days of learning to get you conversational.

    Rescue officials in Poland are working quickly to clear one of the country's highways. The roadway is covered with a sticky brown material. It is blocking cars from both directions.

    What is causing the mess? Milk chocolate. The problems began early Wednesday, after a huge truck carrying many tons of liquid chocolate overturned. Chocolate spilled out. It spread across six driveways of Poland's A2 highway.

    The liquid chocolate solidified（凝固）as it cooled, causing even more difficulties. The accident happened near the western Polish town of Slupca. Bogdan Kowalski is with the fire fighters of Slupca. He told the Associated Press that “the cooling chocolate is worse than snow”.

    Videos published on social media showed rescuers and cleaners were trying to move the sticky brown mess with a bulldozer（推土机）.

    The private Polish broadcaster TVN24 reported that the driver of the truck was taken to a hospital with a broken arm. The accident happened in the morning when there was little traffic. Nobody else was harmed.

    The sticky situation became a hot topic on social media. Some people offered to help the clean-up workers by eating the chocolate themselves.

    Marlene Kukawa is a media officer for Slupea police. She told the New York Times that rescue workers needed to remove the truck from the highway first. “The cleanup”, she said at the time, “will take a few hours or more.” She added that accidents are rare in this part of the A2 highway. And, she told the New York Times, she is sure the area has never experienced something quite like a huge chocolate spill.

    CREATIVE KIDS

    FILM MAKING

    Become a director, scriptwriter(编剧), editor(编辑) and more … all in a week?

    Six half days of film making + six half days of fun activities.

    What's it all about?

Imagine yourself as the new Steven Spielberg or Ridley Scott? Love the cinema, but think you could do better? Or do you dream of being the next Keira Knightley or Johnny Depp? If so, then this is your holiday! You and your group will choose the type of film to make — adventure, fantasy, thriller or comedy. Then you'll create your own film to show at the end of the week. What's more, you'll also take your film home on DVD too!

    Can I do other activities as well?

Yes — every day there's also half a day of activities from our great activity programme, and different entertainment every evening. So you can pack in lots of other new experiences too!

    What do I learn?

    You'll learn the basics of film and sound recording, performing, and script-writing; and how to use sound effects, visual effects and music.

    You'll also learn about the work of a director, before editing your own film.

    Do I need any experience?

    No, our fantastic trained instructors and film industry experts will guide you through the whole process, and give you tips from the professionals.

    Do I need any specialist equipment?

    No, we'll provide all the equipment, from top spec digital video cameras and editing equipment, to costumes and make-up. Just bring your imagination!

    Only￡695 per child!

    Inside Out is one of my favorite Disney / Pixar movies. The story is about a young girl named Riley who moves from Minnesota to San Francisco with her family and how she deals with her emotions (情感) through the move. These five emotions in Riley's brain are Joy, Fear, Anger, Disgust (厌恶) and Sadness. These emotions play a very important role in her life. I can understand because I am an 11-year-old girl and I am very in touch with my emotions and pre-teen feelings.

    The film is extremely beautiful and you couldn't ask for better direction from Pete Doctor. The use of the right colors for the characters is great. For example, Joy is yellow, Sadness is blue, Disgust is green, Fear is purple and Anger of course is red. Sadness plays a main role in the story and it makes me wonder why we are told not to be sad. I think it's important to be sad when the time comes. The end of the movie pretty much got me and the whole audience (观众) (families, couples and even elderly people) in tears and I cried very hard.

    I recommend (推荐) this movie for anyone from 8 to 18 because it has enough joy in it for younger kids to like it even though it does have some sad moments. I believe that adults will like it too. And I give it 4 out of 5 stars because it connects to an older audience even though it is designed for a younger audience. I think younger children can see this, but a parent would have to explain some things to them after the movie.