Best Companies

Shine United (Madison, Wisconsin)

    In the past five years, this Wisconsin-based advertising agency has shared more than $500,000 in profits with its employees through the company's ShineShares program. The agency partnered with the University of Wisconsin's oncology department to develop the Ride, a biking event that benefits cancer research. Employees also get snacks every day, "Beer Thirty" on Thursdays, and Summer Fridays, a program that lets employees leave at noon.

GroundFloor Media (Denver, Colorado)

    The key for workers at this midsize public relations firm in Denver is that employees work anytime, anywhere. Headquarters are in a former warehouse downtown, near Coors Field. The offices are spread around the central space that doubles as a wet bar every Thursday when the company's "bear club" brings in a new brew.

Ergodyne (St.Paul, Minnesota)

    The St.Paul-based company has grown to operating out of a retired storehouse with plenty of natural light. Rules about dressing? "Wear something." Its purpose? To create cool, comfortable, and tough safety workwear for those who need it to get the job done. Ergodyne has around 50 employees, who enjoy hot dish cook-offs, tickets to sporting events, and at least one happy hour every quarter.

Southwest Michigan First (Kalamazoo, Michigan)

    It's family first at this Michigan economic development advising agency. CEO Ron Kitchens says that in the past year, the company has made a push to go green, initially started by the millennial employees who make up half the agency's workforce. A new staff position was created for the purpose of making sure every employee is able to balance working and cheering at their kids' sporting events or going fishing.

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    My mother raised me as best as she could, taking on odd jobs in the neighborhood for money. Still without a father to tell me how to act and what was expected of me, I felt lost. I wandered for years and got involved with tough guys on the East Side of New York. They would fight madly over a dropped coin. They would steal to get what they wanted. I wanted to be like them.

    It was lucky for me that I left the city and entered a world of discipline (纪律), after following my mother's advice. During three years of military service, I had time to rethink my life, and my thoughts often ran to my mother. I realized suddenly just how much of a heartache I must have been to her, how little I had noticed her suffering. When my father left this world, my mother was completely alone. To support us, my mother cleaned apartments and took in washing and ironing from the neighbors. And as she worked hard at this labor, she kept her head high. Each week she would bring a pile of books home from the library and read to us. My mother had wanted nothing more, than for me to turn into an honest responsible man. But I had acted against her. Finally, almost too late I had the sense to feel shame.

    Ten years passed and I returned to the apartment on the East Side. I knew I wouldn't fall back in with the wrong people, although I still wasn't sure where I was heading. My mother, I could tell, was worried about me. In my neighborhood, to become a police officer or a firefighter was a mark of significant social success and achievement. For me it was an opportunity for a real start in life. I wondered if I was up to it, but I knew that it was time to try. When I found myself in the big hall raising my hands to take the firefighters oath (誓言) of office, my mother was sitting a few rows behind with a smile of relief. She knew that at last I was off on life's road and moving steadily. Her smile said, “My job is finally done.”

    Singapore's public transport system is one of the best in the world, so you should have no problem finding your way around like a local. There are three main forms of public transport that you would find in any other major city—trains, buses and taxis.

    TRAINS

    Trains run from 6:00 am to midnight. Single trip tickets start at 80 cents. If you buy an EZ-Link cars for $15, you can ride the trains and buses as you like.

    If you need more information, just call Transit Link on 1800 525 7333.

    BUSES

    There are several bus services in Singapore and fares start at 80 cents. Be sure always ask the driver the cost of your ticket as he can not give change.

    If you need help, just call Transit Link on 1800 525 7333.

    TAXIS

    There are three main taxi companies—City Cab (6552 2222), Comfort (6552 1111) and Tibs (6552 8888). Booking can also be easily by calling the numbers listed above.

    RENTAL CARS

    Driving in Singapore is a pleasure and if you liked to travel at your own pace, renting a car is a good choice. Renting takes away the hassle of getting to places around Singapore. Just sit back and enjoy the city. It also means you'll get to see a lot more that a train or a bus won't let you see.

    For car rental, call Avis on + 65 6737 1668.

    Kettle's Yard, Cambridge

    This modern-art gallery in a Victorian house was founded in the 1950s by Tate Jim and reopened in February following a two-year redevelopment by Jamie Fobert Architects, the team behind the 2017 Tate Steves extension. This means a new cafe, a four-floor education wing and improved gallery space that can accommodate more visitors. The gallery's permanent collection includes works by Joan Miró, Henry Moore and Barbara Hepworth.

    Being Brunel, Bristol

    To celebrate the life and work of famous civil engineer Isambard Kingdom Brunei, Being Brunei will open in March on Bristol's harbourside. The museum will include a range of interactive and entertaining exhibits, including talking portraits of his friends and family and personal possessions, including an 1821 school report. It is a good place for families to strengthen connections.

    Royal Academy of Arts, London

    The RA reopens on 19 May for its 250th anniversary, following a £50m renovation (翻新) with a gallery and expanded exhibition programme. These will include three day-lit galleries, which will host exhibitions with a focus on contemporary art and architecture. The grand frontwall of the Burlington Gardens building has also been restored—possibly the first time it's had a proper clean in its 150 year history.

    V&A, Dundee

    One of the most significant new openings of the year will be Scotland's first design museum and also the first V&A anywhere outside of London on 15 September. The museum building sits on the river Tay. It will celebrate Scottish design and objects in its collection.

    Like people, plants experience stress. And also, like people, the response to that stress can determine success.

    Bad environmental conditions, such as drought, flood, heat and other stresses, affect yields (产量) more than crop pests and diseases. We are trying to find a way to equip plants with the ability to tolerate environmental stress and maintain high yields, said Stephen Howell, a professor of genetics and cell biology.

    Plant cells produce proteins (蛋白质) and ship them to different parts of the cell. Under normal conditions, these proteins are folded into their normal, healthy structures as they are produced. When a plant is under stress, its cells produce poorly folded or unfolded proteins. Then a built-in system senses this and “sets off an alarm in the cell,” said Howell.

    In response to the alarm, another protein (IRE1) starts working and creates a different process which activates (激活) the stress response genes whose products bring about defensive measures that help the plant survive.

    “As it turns out, responses that are activated under stress conditions actually inhibit the growth of plants,” said Howell. “This allows them to preserve their energy to survive the stress conditions.”

    For plants in the wild, this response is a help for survival, he said. In production of agriculture crops, however, this response reduces yields.

    “You don't want crop plants to stop growing,” Howell said. “You want them to continue to grow and produce even though they are under stress.”

    With the new understanding of this stress response, the next step may be to silence the alarm system, said Howell. “What may be important is to disable some of these stress responses. That may make the plant more productive under stress conditions.”

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